246 resultaten
1. To determine the effectiveness of 2 interventions (basic support (A&Cb) vs intensive support (A&Ci) compared to care as usual in CHF patients on time to first major event (HF hospitalisations and death), quality of life and costs…
Findings from both epidemiological and basic research point to the possibility that NSAIDS impede the deterioration in schizophrenia.
The study aims to assess the efficacy (in terms of growth response over the years of treatment, including final height) and safety of a treatment regimen consisting of: 1. Authentic biosynthetic growth hormone (GH) in a dosage of 4 IU/m2/day between…
308-nm Excimer lasertherapy will obtain faster repigmentation after minigrafting than NB-UVB therapy in vitiligo patients.
In the RIO study programme, the efficacy of rimonabant was examined. The next step is to assess the use of rimonabant, its safety and effectiveness in daily practice. In daily practice people also have other diseases, may use other medication and…
Several open-label pilot studies have shown a promising effect of intrapyloric botulinum toxin injection on symptoms in severe gastroparesis. However, data from randomized, double-blind, placebo-controlled studies are not yet available. We intend to…
DBS in the nucleus accumbens can lead to long-term improvement of obsessive-compulsive symptoms and funtioning, without unacceptable side-effects.
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A specific set of variables of impairments are related/ predictive of functional limitations and disabilities. A specific set of variables of functional limitations are related/ predictive of disabilities. Psychological variables (defined by TPB,…
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The on-line intervention will prove to be significantly more effective in improving mood and reducing diabetes-related distress in diabetes patients with minor to moderately severe depression compared to the control condition (CAU, supplementend…
To evaluate the response to adalimumab treatment in TNF-alpha blockade naïve patients and patients who failed prior other anti-TNF-alpha treatment and to understand the mechanisms underlying the clinical response to TNF-alpha blockade.
The intervention lead to: 1. More knowledge about (the use of) prescribed medicines; 2. A better use of medicines during the stay in the hospital and after discharge.
Measurement of airways hyperresponsiveness by mannitol (Aridol©) as compared to methacholine saves time to the lung function technician, while being as sensitive to discern hyperresponsive from normo-responsive, and being at least equally acceptable…
Adherence to diabetes guideines is moderate, especially on educational aspects. Changes in lifestyle is a major element of the patient treatment. Studies on motivational Interviewing show promising results among dieticians. There are no primary care…
The high incidence of cardiovascular disease in patients with end stage renal disease (ESRD) is related with the accumulation of uremic toxins in the middle and large-middle molecular weight range. As online hemodiafiltration (HDF) lowers these…
Based on systematic reviews concerning effective treatments in children with migraine a medical treatment (propanolol) as well as a non-medical treatment (relaxation therapy) appear to be effective compared to no treatment or placebo. however their…
Aetiology of late-onset depressive spectrum disorders may be different from the aetiology of early-onset depression. Concordant with the supposed aetiology of dementia, it has been postulated that chronic low grade immune activation plays a role in…
It is hypothesized that long term disabled persons who participate in the MDR program will return to work and have less mental and/or physical limitations to prevent te pre-disability income. Furthermore an explorative study into the process…
Our hypothesis is that peroperative fluid restriction will lead to a significant reduction of solid phase gastric emptying time ¨C measured by radionuclide scintigraphy-, and a reduction in its related postoperative complications.