722 resultaten
There is clear medical need in pediatric high-grade MDS and JMML to control disease pre-SCT without the disadvantages associated with intensive chemotherapy. So far no agents have been successfully applied in this window, or are specifically…
Een klinisch behandelprogramma met een opnameduur van acht weken gevolgd door een intensief vervolgprogramma voor kinderen (8-19 jr.) met ernstige obesitas is kosten effectiever dan een klinische interventie met een opnameduur van zes maanden en…
Our hypothesis is that routine application of elastic stockings after varicose vein surgery is not beneficial with regard to pain- and physical functioning scores, complications, edema formation, time before returning to work and analgesics…
1. The point of the skin with best possible transcutaneous nerve stimulation correlates with the point of the skin most superficial to the nerves stimulated within a range of 3 mm; 2. Ultrasound will reveal a significant number of sensitive…
6MP treatment in pediatric ALL patients can be improved by developing a pediatric oral drinking solution of 6MP, assessing its bioequivalence, and -when successful- introducing the new formulation nationwide.
The hypothesis to be tested is that the outcome in arm B is better than in arm A.
Binocular patching in combination with posture adherence is superior to posture adherence alone in achieving visualization of the superior fundus quadrants following a vitreous hemorrhage.
We hypothesize that a treatment algorithm that is based on a simple validated measure of health status (CCQ) improves quality of life (as measured on a separate scale) and other classical COPD outcome measurement parameters such as exacerbation…
Computer-tailored safety information combined with personal counseling results in: 1. Improved parents¡¦ child safety behaviors; 2. Improved satisfaction with different elements of intervention.
The primary research hypotheses are: 1. Patients who follow the Onco-Move program will achieve better physical fitness levels, as assessed by objective performance tests, and will report less fatigue than patients in the usual care control group; 2…
Smoking cessation after development of coronary heart disease improves prognosis more than any other treatment and prevents future cardiovascular diseases. This study aims to provide hospitalized coronary heart disease patients who smoke with proven…
External cepahlic version (ECV) of the fetus in breech position is a safe and relative simple obstetric intervention to reduce the incidence of caeserean section for breech position at term. Uterine relaxants can enhance the success rate of ECV with…
This study aims at testing the effectiveness of a web-based self-help intervention for people with mild to moderate suicidal thoughts.
A home-based peripheral muscle training program (Five Basic Exercises program (5BX)) is more effective in [a] increasing exercise capacity (e.g. peak work rate) and [b] patients’ preferred occupational performance when it is preconditioned by…
The hypothesis to be tested that the outcome in arm B is better than in arm A.
Is there a difference in the recurrence rate if you treat a cyst or abscess of the bartholin gland with a marsupialization or placement of a word catheter.
We hypothesize that subjects suffering from hypothalamic dysfunction may have a hyposerotonergic neurotransmission. Therefore we will investigate if there are differences in specific hypothalamic-to-nonspecific [123I]FP-CIT binding ratios using…
In patient with clinically suspected appendicitis, imaging is needed to substantiate the clinical diagnosis. Imaging accuracy of US and CT is suboptimal, and the associated use of ionizing radiation and iodinated contrast medium are major drawbacks…
Assess of the effect of HD colonoscopy alone or when combined with different I-scan functions compared to standard colonoscopy with respect to adenoma detection rate.
Patients undergoing a minimally invasive oesophagectomy have fewer morbidity, a shorter duration of the intensive care unit (ICU) admission and a better quality of life than following the traditional approach.