1612 resultaten
The use of a new protocol of exercise testing with use of blood pressure measurement, near infrared spectroscopy and pedal force measurement will improve the diagnostic value of the current decision algorithm used to diagnose functional iliac flow…
Pelvic floor muscle training supported by vaginal and abdominal biofeedback, serious games and a web-portal is non-inferior to pelvic floor muscle training alone.
Our hypothesis is, that the extrinsic mechanism in the etiology of SIS is only valid for a subgroup of patients; complaints of SIS can be caused by 1) a pathologic pattern of arm-scapula movements caused by a disrupted balance in muscle forces,…
Postoperative pain, further blood loss, onset of delirium and wound discharge are unfavorable factors that can prolong hospital time, delay mobilization and necessitate transfusion. Cryotherapy and pneumatic compression are suggested to minimize…
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It is expected that the drink will contribute to an improved postprandial glycaemic response and to an increase of satiety in subjects with type 2 diabetes mellitus.
The primary objective is to determine whether JWH-018 can be safely administered in healthy volunteers in doses up to 3 mg. Therefore participants will be continuously monitored by a medical doctor and vital signs, laboratory clinical safety and…
We hypothesize that induction of labour in patients with gestational hypertension, deteriorating chronic hypertension or preeclampsia between 34 and 37 weeks reduce the maternal morbidity but might increase the RDS rate in neonates, compared to…
We hypothesize that the CPA Talking-with-children-intervention will have a beneficial effect on the mental health and quality of life of maltreated children. We expect that children who participate in the CPA investigation (CPA Talking-with-…
We hypothesize that it is possible to culture circulating tumor cells obtained by leukapheresis into organoids.
Synflorix (PCV10) and Prevenar-13 (PCV13) are comparable in inducing cellular and humoral immune responses in Dutch infants for the 10 overlapping serotypes in the vaccines. Differences are expected for three serotypes that are present in Prevenar-…
The aim of this study is to pass of the care for patients with fibromyalgia more efficiently through the cooperation of the rheumatologist and the nurse specialist. Because of this, the rheumatology outpatient department can be relieved partly,…
It is expected that the urinary and serum level of intestinal fatty acid binding protein (I-FABP) and the urinary level of Claudin-3 have prognostic relevance for early identification of patients at risk for intestinal ischemia-related morbidity or…
Cap-assisted colonoscopy may improve the adenoma detection rate in CRC screening participants.
A nutrient dense infant formula promotes growth more effectively than current practice.
We hypothesize that ingestion of potato protein increases muscle protein synthesis rates at rest as well as during recovery from exercise in young healthy males. We hypothesize that the muscle protein synthetic response to the ingestion of potato…
Evidence based medicine is the standard for current clinical practice. Guidelines and decision rules are developed to support medical decision making. Application of decision rules are supposed to improve efficiency and quality of care by early…
Patients with a BMI > 30 kg/m2 in the ICU have a higher incidence of pressure ulcers and wound infections in the ICU compared with patients with a BMI 18-25kg/m2. They develop them sooner during admittance and the severity and time to…
The study aims to assess the efficacy (in terms of growth response over the years of treatment, including final height) and safety of a treatment regimen consisting of: 1. Authentic biosynthetic growth hormone (GH) in a dosage of 4 IU/m2/day between…
Frequently people experience nausea and vomiting following surgery. There are several pharmacologic interventions possible; there is no rational evidence-based approach available. In this study the current therapy regaring PONV and its efficacy in…