143 resultaten
We hypothesize that aromatase-inhibitors will have lower efficacies in the presence of an abundant estrobolome and high ß-glucuronidase activity. It’s also unclear whether microbiota influences intestinal absorption of tamoxifen’s related metabolite…
We hypothesize that a certain shear load threshold exists, where an increase in the cytokine IL-1a is observed.
Hypothesis 1: Adolescents who are exposed to a vlog intervention to promote physical activity will be more physically active compared to adolescents who are not exposed to a vlog intervention. Hypothesis 2: Adolescents who are exposed to a social…
Persons with intellectual disabilities remain dependent on a caregiver for various aspects of their life, often including coping with emotions and stress. It is therefore crucial that parents and other caregivers of persons with ID are aware of…
The effects of a video game targeting inhibitory control in a social context will be tested in a Dutch sample of adolescent- and young adult smokers (between the ages of 16 and 26). It is expected that the adolescents and young adults who receive…
- How effective are the Acts of Kindness exercises with and without reflection compared to an active control condition and wait-list condition on mental well-being, flourishing, positive relations, gratitude, positive and negative emotions, optimism…
1.We expect participants in the experimental condition to show a reduced gmbling behaviour 2. We expect participants in the experimental condition to show a decrease in approach bias towards gambling cues, and weaker approach implicit associations…
the prognosis of patients with severe RV failure after LVAD-implantation, post-cardiotomy or post-MI is grim, as medical treatment options are scarce. In a previous study, treatment with the Impella RP has been proven to be safe, feasible and…
Pelvic floor muscle spasms resulting in chronic pelvic pain may occur as a primary event or secondary to a physical, psychological or pathological factor. First-line treatment consists of pelvic floor physiotherapy. When first-line treatment fails,…
It is hypothesized that Active+ improves cognitive functioning in elderly with limited mobility through improvements in physical activity. As the literature is inconclusive on characteristics a PA program minimally needs to have in terms of type and…
1. We first propose that in advanced TC, not only tumor-associated macrophages (TAMs), but also circulating monocytes and bone marrow (BM) myeloid progenitors are functionally reprogrammed by tumor-derived metabolites even before their recruitment…
Patients undergoing superior capsule reconstructions (SCR) for superior shoulder instability will experience less pain (decrease of at least 2 points) and improved function.
Hypothesis 1: Participants in both conditions (experimental and placebo) will show a reduction in gamble problem severity immediately post-intervention and at 3-and 6-month follow-ups. However, participants in the experimental condition will show a…
1. The use of food supplements containing vitamin C with quercetin and other flavonoids can reduce inflammation clinically (assessed by means of periodontal parameters), and systemically (assessed by means of biomarkers), in patients diagnosed with…
Based on our primary results we do not expect anatomical difference between the two groups. However, we expect to see more erosion as compared to 1 year of follow-up.
At the end of the study we should be able to publish an internationally accepted, multidisciplinary, evidence based guideline on the management of trigger fingers
1) Epidemiology of postoperative pain What is the correlation between pain intensity scores and type of surgical procedure in relation to patient characteristics and analgesia? Is it possible to specify surgical procedures indicating its pain…
It is hypothesized that SADI after sleeve gastrectomy for additional weight loss is superior to a gastric bypass as secondary procedure
PPIs are prescribed very frequently and might cause potentially severe hypomagnesaemia. We carried out a study focussing on the prevalence of hypomagnesaemia in geriatric inpatients using PPI and evaluated risk factors contributing to this effect.…