199 resultaten
Evaluating the smell of e-liquids from different brands with similar flavors allows us to select the brand that most closely represents this particular flavor.
Renal transplant patients are at increased risk of colonization and infection with multidrug resistant Enterobacteriaceae (MDRE) due to medications that modify their immune systems, increased healthcare and antibiotic exposure, and surgical…
1. During cold exposure, we aim to stimulate (lipid) metabolism of BAT and muscle tissue. During this cooling process we will perform a two meal test to study the effect of cold exposure on triglyceride metabolism. 2. We expect that after cold…
Glycocalyx volume is diminished in subjects with premature atherosclerosis.
We hypothesize that aromatase-inhibitors will have lower efficacies in the presence of an abundant estrobolome and high ß-glucuronidase activity. It’s also unclear whether microbiota influences intestinal absorption of tamoxifen’s related metabolite…
We hypothesize that a certain shear load threshold exists, where an increase in the cytokine IL-1a is observed.
We hypothesize that the underlying mechanisms of the varying response in multiple parameters within an individual can be attributed to variability in the causal path between drug administration, drug tissue distribution, and tissue receptor…
The induction of immunity might be slower in older persons than in younger individuals. This could influence the occurence of adverse events induced by the vaccine.
Vitamin D improves muscle-mass and -strength which improves overall quality of life in patients with low serum vitamin D levels.
We hypothesize that performing a total laparoscopic hysterectomy with same day discharge is safe and leads to equal levels of patient satisfaction when compared to admittance for 1 night.
It is hypothesized that Active+ improves cognitive functioning in elderly with limited mobility through improvements in physical activity. As the literature is inconclusive on characteristics a PA program minimally needs to have in terms of type and…
1. We first propose that in advanced TC, not only tumor-associated macrophages (TAMs), but also circulating monocytes and bone marrow (BM) myeloid progenitors are functionally reprogrammed by tumor-derived metabolites even before their recruitment…
In the Netherlands, 90% of the patients with gout are managed by general practitioners but most research has been done in secondary care. In primary care there are questions on the clinical relevance of long-term uric acid lowering treatment of gout…
"De Nieuwe Toekomst" will empower female victims of intimate partner violence by making them financial independent which reduces the risk of intimate partner violence victimisation
To determine the influence of optical quality on perimetry for phakic and pseudophakic healthy and glaucoma patients. To determine the influence of CLE on perimetry and optical quality for PAC patients.
The purpose of the Liberté One study is to assess procedural, clinical and angiographic outcomes of the provisional T-stenting approach with the Taxus Liberte stent implanted in complex lesions (with side branch involvement). The Taxus Liberte stent…
Pelvic floor muscle spasms resulting in chronic pelvic pain may occur as a primary event or secondary to a physical, psychological or pathological factor. First-line treatment consists of pelvic floor physiotherapy. When first-line treatment fails,…
Theoretically there are many advantages of using the Fixion ® IM Humeral nail, like a significant reduced surgical and fluoroscopic exposure time. The procedure is simple and minimal invasive. No interlocking screws are needed, thus there is a…
Hypothesis 1: Adolescents who are exposed to a vlog intervention to promote physical activity will be more physically active compared to adolescents who are not exposed to a vlog intervention. Hypothesis 2: Adolescents who are exposed to a social…