969 resultaten
When young visual impaired children can participate in a training (game) in wich a magnifier is used, they learn to handle the magnifier (fine motor skills) they learn to observe small symbols (visual behaviour) and they become interested in the…
As a result of the intervention we hypothesize that: Due to a tailored consultation provided by a counsellor, containing information on the causes and consequences of DM2 (with emphasis on familial risk) (intervention group compared to control…
The hypothesis to be tested is that the outcome in arm 2 is better than in arm 1.
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Ezetimibe monotherapie lowers LDL-C levels, plant sterol levels and inflammatory markers in young children with familial hypercholesterolemia.
The addition of concurrent and adjuvant chemotherapy to postoperative radiation therapy will increase 5-year overall survival and failure-free survival of patients with high-risk and advanced stage endometrial carcinoma.
Find the best predictive biomarker for respons to treatment.
To study whether in women with suspected ectopic pregnancy with low but plateauing serum hCG concentrations additional treatment with systemic methotrexate in a single dose intramuscular regimen is superior over expectant management in terms of…
Excluding PE by a CDR indicating PE unlikely, assessed by the Wells simplified decision rule, combined with a normal D-dimer is safe and efficient.
Insulin detemir, when injected once daily at an individually appropriate time (either before breakfast or at bedtime), provides superior glycaemic control to insulin glargine injected indiscriminately at bedtime in patients that had clearly…
Homeless patients with severe mental illnesses have to deal with a broad spectrum of problems. Besides the housing problems they have poor physical and mental health, none or low financial income, difficulties in fulfilling social obligations, have…
A randomized double blind placebo controlled trial for the use of intravenous immunoglobulin to reduce the number of exchange transfusions in Rhesus disease of the neonate.
Early antipyretic therapy reduces the risk of death or dependency in patients with acute stroke, even if they are normothermic
The aim of this study is to explore the incidence of MTX related gastro-intestinal in a large cohort of JIA patients. Secondly, we want to investigate the effect of psychological behavioural therapy or switch to parenteral MTX dosing to ameliorate…
The intervention increases advice giving of dental professionals, the number of patients having quit smoking and the number of quit attempts.
Conform components are beneficial for motion coordination and reducing high rim-loads, while non-conform components are beneficial in reducing high humerus–to–scapula impulses (impact forces).
The use of DALK and PLK may lead to more efficient use of donor material and could theoretically decrease the current discard rate of donor tissue of 64.8% to 25% and shorten the waiting time from 6 months to 1 month. For PLK, we estimate that the…
The computer-tailored health information in combination with personal counselling leads to: 1. Improvement of health behaviors; 2. Improvement of parental satisfaction with well-child care visits; 3. Improvement of well-child care provider…
The equations used by most current algorithms are usually based on a simple pharmacodynamic model, which implies a linear function between the INR and the dosage. Our new algorithm consists of two sub models in which the first sub model describes…
To demonstrate superiority over time in treatment of pain of best medical practice with adjunctive SCS Therapy compared to best medical practice without SCS Therapy in patients with chronic diabetic neuropathic pain as measured by VAS score.