969 resultaten
The intervention will primarily effect the level of patient control with regard to glycemia, lipid levels and blood pressure. We will expect a substantial decline in the occurrence and severity of complications and mortality and an improved quality…
We hypothesize that the use of Carbon Dioxide (CO2) reduces the incidence of (air) microembolism during aortic arch surgery, and that it also positively influences the gross neurologic and/or the neurocognitive outcome of this kind of surgery.
rt-PA administration by retinal branch vein way in CRVO patients improves final BCVA.
The aim of the study is to optimize therapy of migraine patients, according to the Dutch GP Guideline for headache and consequently reduce the use of triptans. The project will explore the costs and effects of a proactive approach of patients with…
Children born small for gestational age (SGA) might be at increased risk for developing hypertension, cardiovascular disease and diabetes mellitus type 2. It has been shown that those SGA children with relatively higher GH levels during an overnight…
Participation in supportgroups leads to an improvement in quality of life, social support, social network, self-efficacy and self-esteem.
Fluoxetine has in animals and cell cultures neuroprotective properties. We test whether fluoxetine is able to reduce progression in patients with multiple sclerosis.
Epidural anesthesia is superiour to general anesthesia considering pain control, blood loss, urine retention, recovery duration and general well being for the patient.
1. High dose of PEG is more effective and more tolerable in the treatment of fecal impaction compared to rectal enemas; 2. Fecal impaction results in a delayed colonic transit time, which will improve during successful disimpaction.
Assuming that the effects on Parkinson's disease symptoms and dyskinesias, and the rates of procedure-related and device-related complications are almost equal, then continuous bilateral GPi DBS may produce greater functional improvement than…
Combination therapy of steroids plus MTX induces remission faster and will therefor reduce steroid toxicity and disease damage.
1. To establish in a randomised controlled trial if screening for lung cancer by multi-slice low-dose CT in high risk subjects will lead to a 25% decrease in lung cancer mortality; 2. To estimate the impact of lung cancer screening on health…
GPs play a central role in providing palliative care (PC) in the Netherlands. Good GP-patient communication is essential for the delivery of high quality care. Communication in PC is difficult, involving a mix of physical, psychosocial, and…
Client-centred occupational therapy according to the Occupational Performance Process Model will be more effective in improving daily functioning and societal participation of patients with multiple sclerosis than usual-care occupational therapy.
urge incontinence is caused by overactivity of the detrusor muscle of the urinary bladder. Electrical stimulation of the pelvic floor muscles can suppress detrusor overactivity. The miniaturo tm-i system is designed to deliver mild electrical…
Comparison of two new techniques for detection of small bowel pathology: MR enteroclysis and videocapsule enteroscopy with double-balloon enteroscopy with respect to diagnostic yield, accuracy of findings, and patient preference.
HIV infected patients receiving HAART have an increased risk for cardiac events/disease. In HAART naive patients increased arterial stiffness is substrate for this higher risk. In this study we investigate whether increased risk for cardiac events…
Folate supplementation improves microcirculatory function in subjects susceptible to microcirculatory dysfunction.
Bracing patients with adolescent idiopathic scoliosis in an early stage results in at least 5 degrees less mean progression of the curvature compared to the control group after two years of follow up.
By its pharmalogical action it is likely that aspirin improves ovarian perfusion, uterine perfusion and reduces endometrial restraint on the implanting embryo. Therefore the hypothesis of this study is that the use of low dose aspirin in IVF…