495 resultaten
the correspondence between orosensation of sweetness and post-oral sensation of calories influences resting energy expenditure, cerebral blood flow and gastric emptying, and more specifically that the “not sweet enough” beverage, that contains more…
The aims of the study are: To investigate the short-term effectiveness of antecedent and consequent behavioral teacher training techniques for teachers of children attending regular primary school (class 3 to 8, six to thirteen years old) with (…
Cabazitaxel is a tubulin-binding taxane drug that improves survival of patients with docetaxel-metastatic-castration-resistant prostate cancer (mCRPC). Unfortunately, cabazitaxel is not effective in all patients and can have serious side effects.…
This overall study aims to evaluate the effects of cardiology PC+ centre on the Triple Aim outcomes. The underlying premises of the researchers on the effects of the intervention are that the cardiology PC+ centre will result in an (at least)…
To investigate the possibility to predict chemotherapy response using proliferation assays.
Patients that receive breast conerserving therapy due to breastcancer with an oncoplastic reconstruction by the plastic surgery are more satisfied with their breast compared to patients receiving breast conserving therapy without a reconstruction.
Persons with intellectual disabilities remain dependent on a caregiver for various aspects of their life, often including coping with emotions and stress. It is therefore crucial that parents and other caregivers of persons with ID are aware of…
The hypothesis of this trial is that the implementation of a best practice algorithm for postoperative care focusing on early detection and step-up management of postoperative pancreatic fistula results in a lower rate of major complications and…
We believe that by engaging the target group in the process of intervention development, more effective intervention targeting children’s physical activity and dietary behaviors can be developed.
A decline of intra-tumoral concentrations over time could be the first sign of the development of drug resistance by the tumor. In this exploratory study we will investigate the relationship between plasma and intra-tumoral paclitaxel concentrations…
The effects of a video game targeting inhibitory control in a social context will be tested in a Dutch sample of adolescent- and young adult smokers (between the ages of 16 and 26). It is expected that the adolescents and young adults who receive…
Acid-reducing drugs, such as PPIs, may profoundly decrease solubility and, as a result, (negatively) affect the bioavailability of afatinib. Since a PPI is often used concomitantly during afatinib therapy, this DDI confronts physicians, patients,…
To evaluate the anti-inflammatory effects of 3 months statin therapy on vessel wall inflammation by means of FDG PET/CT in patients with CKD.
An early mobilization program in critically ill children reduce the consumption of sedatives and opioids and the prevalence of delirium.
We hypothesize that the range of motion of the hallux is limited during gait in patients with hallux rigidus (HR). In addition, we hypothesize that patients with HR will compensate this loss of motion of the hallux by increasing joint motion in the…
Most studies that aimed to discover new IBD biomarkers on a protein level have mainly focused on plasma/serum. However, recent studies suggest that analysing material closer to or directly from the location of disease may yield higher concentrations…
We expect that the older patients with SMI have more somatic health problems, disorders and complaints, compared to the adult patients with SMI.
Combining factors will enable prediction of successful long-term video-EEG monitoring and of adverse effects, related to antiepileptic drug withdrawal.
Epidral analgesia has superior pain management outcomes. On the other hand we hypothize EA requires more aggressive hemodynamic support, leading to higher risk of postoperative complications.