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Inhibition of TNF-alpha in IPF (idiopathic pulmonary fibrosis) will affect inflammatory and pro-fibrotic cytokine expression and thereby will slow-down disease progression in IPF
Based on the literature and preliminary studies three key elements for GP-patient communication in PC were identified: Availability, Active listening, and Anticipating (AAA). Existing GP residency training programmes on communication in PC are in…
The objective of this study is to evaluate a ‘result oriented’ smoking cessation program (‘Silver or Gold’) for COPD patients in which treatment goals are signed up in a doctor-patient contract.
Arthrocentesis of the temporomandibular joint as initial treatment of arthropathy is more cost-effective than usual care.
The use of progestins in combination with estrogen is associated with a reduced incidence of colorectal carcinoma (CRC)1,2. Also, incidental literature has reported a coincidence of the start of oral contraceptive agents with reduction in polyp…
To determine whether involved field radiation therapy (IFRT) can be eliminated based upon early and complete response to multiagent chemotherapy To determine whether the addition of an additional two cycles of chemotherapy (DECA) can improve outcome…
Perioperative Ketotifen prevents and/or reduces postoperative ileus
The recurrence risk after endovenous laser treatment is less than after stripping of the long saphenous vein performed under local anaesthesia.
The administration of probiotics to breastfeeding females exert a direct influence on the development of the infant gut microflora through the transference of selected strains.
Brain activity in people with schizophrenia differs when compared to brain activity of people who do not have this condition. There is evidence that the negative symptoms of schizophrenia are related to reduced cortical activation involving the…
We hypothesise that aspirin 100mg at bedtime decreases tension by nocturnally lessening increase of the renin-angiotensin-aldosterone system, enhancing NO bioavailability, lessening autonomous nervous system activity or inhibiting COX-1 dependent…
PCI will prevent brain metastases, even for patients with other sites of failure, and will improve the neurological disease-free survival, and hence quality of life. PCI will also be cost-effective.
We hypothesize that endoscopic resection (ER) of early neoplasia arising in Barrett esophagus (BE) using the multiband mucosectomy (MBM) technique is equally effective in removing early neoplasia, but may be faster, cheaper and possibly safer than…
The action of statins in CRC is dependant on the expression of elements of the BMP pathway.
The intervention group, receiving a lifestyle intervention, will significantly improve physical activity and dietary behavior, and thus prevent weight gain compared to the control group at the short (6 months) and the longer term (12 months).
Is transmural care for hand eczema by a specialized multidisciplinary centre (cost)effective as compared to usual care?
Driving performance after administration of zopiclone 7.5 mg is not different between patients complaining of insomnia and frequently using hypnotics, insomnia patients not frequently using hypnotics and matched healthy controls.
The average VISA-A score is higher in the patient group treated with eccentric exercise therapy in combination with a PRP injection in comparison with the group treated with a saline injection in combination with eccentric exercises.
Patients with a poor prognosis should get a cheaper plastic stent and patients with a longer prognosis shoud get a more expensive metal stent.