427 resultaten
We hypothesize that by using different imaging techniques, we can give a good characterization of the bone marrow microenvironment in advanced-stage myelofibrosis, before and during treatment with ruxolitinib.
With implementation of the AWR we expect a reduction in the total amount of radiographs requested, without missing any clinical relevant fractures. We also expect a reduction in overall waiting times at the ED and a total amount of cost savings…
Fatigue affects central nervous system function and, in the setting of the medical profession, could influence specialist performance, patient care and safety. ln contrast to other industries, for example the aviation industry, there are no "…
About 10-15% of the population suffers from chronic insomnia. Structurally poor sleep can have unpleasant consequences for people's health and quality of life. Therefore, proper treatments are of great importance. Fortunately, Cognitive…
H1: the exercise intervention is effective in reducing (work-related) fatigue H2: the exercise intervention is effective in improving (work-related) self-efficacy, sleep quality, work ability, cognitive functioning, and aerobic fitness.
Children aged 4 to 6 years in the intervention group who have received the GigaGaaf! intervention have a different oral health than children aged 4 to 6 years from the control group who have received care as usual. Parents of the children aged 4 to…
Monitoring a patient’s oxygen status during anesthesia using pulse oximetry is essential. The new Oxygen Reserve Index (ORI) may help provide clinicians real-time visibility to oxygenation in a moderate hypoxic range and serve as a warning of an…
Aim of the study is to determine how often muscle strength measurements should be repeated, using a hand-held dynamometer to obtain a maximal muscle strength measurement
Delegation of clozapine monitoring tasks to a Nurse Practitioner (condition A) is at least as safe as Treatment As Usual: physicians perform monitoring tasks themselves (condition B).
Painreduction for 67% of patients with a locally advanced or local recurrent pancreatic carcinoma through a short radiotherapy scheme (single arm phase 2 study)
Informed consent procedures and information provision differs between different transplantation centers and transplantation professionals in The Netherlands. Donor knowledge and satisfaction may be influenced by the manner of information provision…
Recently, (changes in) the gut microbiome (flora / bacteria) have been associated with obesity and insulin resistance, and other cardiovascular risk factors or atherogenic processes. Venous thrombosis shares these risk factors, probably by a shared…
There seems to be a biphasic process of bone mineral density (BMD) changes in osetoarthritis (OA). An increased bone mineral density (BMD) and a specific distribution of BMD in the cortical of the subchondral plates and below in the trabecular bone…
Several reasons for clozapine discontinuation are known, but the current evidence identifying patients who are at risk of discontinuation of clozapine is small and not always consistent. Also cultural differences may question if international…
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The hypothesis is that minimal invasive surgical ablation through video assisted thoracoscopic surgey as a primary treatment in patients suffering from (longstanding) persistent atrial fibrillation is superior to transvenous catheter ablation
The null-hypothesis predicts that Inlife is not feasible. The alternative hypothesis predicts that the Inlife intervention is evaluated as being feasible. We expect the alternative hypothesis to be true. Inlife will be feasible and minor revisions…
1) The knowledge of the legal aspects of health care and medical negligence/errors among medical residents is larger in the intervention group than for the control group 2) The flipped classroom model is effective as a teaching method in post…
The EuraHS-QoL questionnaire is a valid instrument to measure quality-of-life before and after ventral hernia repair.
Refinement of the CHIP prediction rule will lead to a more efficient use of head CT in patients with minor head injury