256 resultaten
Kidney transplantation is the only treatment offering long-term benefit to patients with chronic kidney failure. Urological complications after kidney transplantation, such as urinary leakage and ureteral strictures, are associated with significant…
We hypothesize that depletion of carnitine occurs during infusion of oxaliplatin, due to increased renal loss. This secondary carnitine deficiency may contribute to the development of CIPN.
The CPCHILD-18+ is sufficiently tested for its psycometric characteristics to be used in clinical practice and research
Primary hypothesis is that MRDTI will demonstrate acceptable sensitivity and specificity for the diagnosis of acute SVT and the differentiation between acute and chronic SVT.
The hypothesis addressed in this project is that serum calcification propensity is a predictor of coronary artery calcification progression.
The hypothesis states that the time tom complete an emergency airway with Cricath device is significant faster than with Quicktrach device, which will be studied on porcine cadaver models. In the second outcome, the hypothesis states that there is…
Fatigue is expected to be the most prevalent symptom in patients with ILD (IPF and sarcoidosis), next to dyspnoea. Frequency of moderate to severe fatigue in patients with ILD is unknown. In addition, possible correlates of fatigue, including age,…
Traditionally, all surgically removed appendices and gallbladders are sent to the department of pathology for histopathological examination. This is most likely not necessary in appendices and gallbladders that are not suspicious for a malignancy…
The primary hypothesis is that playing the serious game 'You & I' will be associated with an improvement of the mentalizing abilities in adults with mild to borderline intellectual disabilities. The secondary hypothesis is that…
Poor glycaemic control, indicated by an elevated HbA1c, is correlated to poor postoperative outcome in patients with diabetes mellitus undergoing surgery. However, improving glycaemic control before surgery has not been extensively studied so far.…
End stage kidney disease (ESKD) ranks among the most severe chronic non-communicable diseases with an unmet medical need, given the high (between 10% and 20%) and stable annual mortality rates in ESKD patients treated with dialysis. Kidney…
Medication reconciliation using an e-health application is as good as structured medication reconciliation by a pharmacy technician
Biperiden deteriorate the cognition that biperiden will be used for a challenge model.
Fecal Microbiota transplantation, applied through a nasoduodenal tube will eliminate intestinal carriage of VRE after a six month follow up period.
SSA are effective in decreasing transfusion requirements and improving quality of life while being cost-effective.
Flow cytometric analysis of circulating melanoma cells after enrichment by leukapheresis: FAME study
We hypothesize that presence of CMCs could be a potential prognostic biomarker in patients with melanoma, in particular for patients with stage III melanoma. Given the low numbers of CTCs in this latter setting, we therefore aim to optimize a…
The smartphone connected MED as AAF is a valid screening instrument for application in transmural care in the Netherlands.
• To determine between-subject and within-subject variability of the study endpoints. • To determine the differences between subjects and healthy controls regarding the study endpoints. • To identify suitable endpoints for future clinical trials in…
Following the implementation we expect an increase in number of patients receiving pain medication, an increase in analgesic dosages, decrease of PAIC scores. With regard to the process evaluation we expect good interrater reliability and a…