2441 resultaten
Dietary management of nutrient deficiencies with the medical food under study has a positive effect on cognitive performance in patients with prodromal Alzheimer's Disease.
The hypothesis is that infants who receive the Infant Behavioral Assessment and Intervention Program (IBAIP) will be able to regulate themselves better and that disabilities will therefore be prevented or develop to a less serious degree.
1. There is no difference in HRQoL using a Hb transfusion trigger of 7.2 gr/dl compared to Hb transfusion trigger of 9.6 gr/dl; 2. A Hb transfusion trigger of 7.2 gr/dl leads to a diminished use of RBC transfused compared to a Hb transfusion trigger…
There is a clinically and statistically significant difference in functional ability and progression of radiological joint damage after two years of follow-up in patients with early RA who receive initial combination therapy, combination therapy…
The incidence of gastric cancer has been declining steadily since the 1930s, but it remains a major cause of cancer death in the Western world. The high mortality rate reflects the prevalence of advanced disease at presentation. The five-year…
The systemic treatment of rheumatoid arthritis with anti-TNF-a is very successful. In a number of case reports varying success rates of intra-articular injections with the TNF-a blocking agent infliximab have been reported. In this study we want to…
The hypothesis is that increasing energy and protein intake in these children will stimulate the rate of protein synthesis, decrease the rate of (muscle)protein breakdown, lead to increased net protein accretion, avoids weight loss and promotes…
Uterine cavity evaluation and subsequent resection of endometrial polyps in women with postmenopausal bleeding and endometrial thickness of more than 4 mm will lead to less recurrent bleeding compared to women in whom such is not performed.
In a sample of COPD patients with clinically relevant problems in four main domains of health status (physiological functioning, symptoms, functional impairment and quality of life) a motivational intervention conducted by a pulmonary nurse will…
Pregnancy rates will not differ between patients with a positive and negative result of the PCT.
Het effect onderzoeken van acute verhoging van groeihormoon waardes op cognitief functioneren in gezonde mensen, en uitvinden of de relatie tussen groeihormoon en cognitie direct of indirect is. Doel van het onderzoek: We willen de acute effecten…
There are predictive markers of treatment response (or non-response) at baseline or during early beginning of treatment?
The hypothesis of this study is that hysteroscopic treatment of hydrosalpinges with essure devices is as effective as laparoscopic salpingectomy with respect to subsequent IVF-ET outcomes but is related to less burden (in contrast to laparoscopic…
Higher doses of statins will result in additional improvement of the diabetic lipid profile.
The change in biochemical parameters of bone and colleagen metabolism during a shortterm GH dose-response study predicts the long-term effect of GH on growth. Idiopathic short stature is partially explainable by an abnormal tissue responsiveness to…
Hepatocellular Carcinoma (HCC) is the 5th most common solid tumor worldwide. Overall mortality from HCC is high with almost 600,000 deaths worldwide in 2002. Although various chemotherapy regimens are available based on doxorubicin, cisplatin or…
It will be expected that the implementation of the intervention Preventure will reduce alcohol use (binge drinking) by young adolescents (12-16 year).
The helical geometry of this vascular access prosthesis reduces flow stagnation and low shear stress at the venous anastomosis resulting in diminished neointimal hyperplasia.
To assess the current indications for URS and the treatment outcomes in terms of the stone free rate.
The purpose of the study is to conduct a randomised controlled trial with the training course 'Less stress through mindfulness' as an intervention to study the: 1. Effectiveness in terms of reduction of psychological symptoms (depressive…