3040 resultaten
The intervention will primarily effect the level of patient control with regard to glycemia, lipid levels and blood pressure. We will expect a substantial decline in the occurrence and severity of complications and mortality and an improved quality…
We hypothesize that the use of Carbon Dioxide (CO2) reduces the incidence of (air) microembolism during aortic arch surgery, and that it also positively influences the gross neurologic and/or the neurocognitive outcome of this kind of surgery.
Pulse oximetry is a non-invasive method allowing monitoring of the oxygen saturation of a patient. For many years now, it has been used in secondary care with great success. Recently, it is noticed that pulse oximetry is used more often in the…
To test the hypothesis that acetaminophen is a safe and effective analgesia in neonates and to determine the optimal loading dose of intravenous Acetaminophen in neonates of different gestational age subgroups.
rt-PA administration by retinal branch vein way in CRVO patients improves final BCVA.
Most medications prescribed for the treatment of asthma have a variable responsiveness. It is clinically relevant to be able to predict responsiveness to a specific medicine in an individual patient. There is no such test currently available.…
The aim of the study is to optimize therapy of migraine patients, according to the Dutch GP Guideline for headache and consequently reduce the use of triptans. The project will explore the costs and effects of a proactive approach of patients with…
Dietary management with the medical food under study has a positive effect on muscle strength and physical functioning in elderly.
We hypothesize that treatment of patients with acute ischemic or hemorrhagic stroke and a body temperature of 36,5°C or above with paracetamol in a daily dose of 6 g for three consecutive days, leads to improved functional outcome. At least 50% of…
One of the challenges in paediatric anaesthesia is to minimize distress for children in the operating room environment and to facilitate a smooth induction of anaesthesia. Pre-anaesthetic medication reduces the risk of adverse psychological and…
Children born small for gestational age (SGA) might be at increased risk for developing hypertension, cardiovascular disease and diabetes mellitus type 2. It has been shown that those SGA children with relatively higher GH levels during an overnight…
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We hypothesize that public involvement results in greater agreement between quality indicator choice and public priorities.
The primary objective of this study is to determine if bezafibrate can reduce VLCFA in plasma, lymphocytes and erythrocytes and C26:0-lysophosphatidylcholine in patients with X-linked adrenoleukodystrophy.
Participation in supportgroups leads to an improvement in quality of life, social support, social network, self-efficacy and self-esteem.
Fluoxetine has in animals and cell cultures neuroprotective properties. We test whether fluoxetine is able to reduce progression in patients with multiple sclerosis.
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Modern dressings containing silver are more effective than topical antibiotic treatment for healing of PEG-site infections.
Overweight and obesity are already prevalent in 4- till 8-year-old children. Obesity-inducing behaviours in young children have been found to track throughout the life span. Acknowledging the lack of effective interventions aimed at preschool…