5157 resultaten
In the RIO study programme, the efficacy of rimonabant was examined. The next step is to assess the use of rimonabant, its safety and effectiveness in daily practice. In daily practice people also have other diseases, may use other medication and…
The self-help intervention Happy@Work will reduce symptoms of depression. The self-help intervention Happy@Work will be cost effective.
Several open-label pilot studies have shown a promising effect of intrapyloric botulinum toxin injection on symptoms in severe gastroparesis. However, data from randomized, double-blind, placebo-controlled studies are not yet available. We intend to…
Een predictor vinden in de vorm van ferritine bij diagnose/leeftijd bij diagnose die het aantal aderlatingen per jaar in onderhoudsbehandeling van hemochromatose patienten kan voorspellen
The hypothesis to be tested is that arm B is tolerable and that the outcome in arm B is better than in arm A.
1. ICVAD removal, followed by six months of silicone gel sheet use, will result in a scar width within the normal range, and normal scar structure, and thus will be superior to two months of silicone gel sheets and no gel sheets; 2. A smaller and/…
Mechanical bowel preparation (MBP) is common practice in elective colorectal surgery. In recent literature the value of MBP is subject of discussion. This non-inferiority, randomized study evaluates the value of MBP before colorectal surgery.
We hypothesize that peripheral perfusion targeted fluid management (PPTFM) might prevent excessive fluid administration, leading to less formation of tissue edema, less respiratory dysfunction and shorter duration of mechanical ventilation.
An intervention consisting of a set of specific fatigue reducing and health enhancing advices will lead to less fatigue and sickness absence in airline pilots. Following the intervention and the accompanying advices will lead to pilots reporting…
-Six weeks of treatment with a supplementary low dose of clonidine to the current medical treatment of clozapine resistant patients will effectively reduce symptom severity and cognitive impairments in therapy resistant schizophrenia patients -…
The purpose of the study is to conduct a randomised controlled trial with the onlinecourse 'Voluit Leven' as an intervention to study the: 1. Cost-effectiveness in terms of reduction of psychological symptoms (mood symptoms and disorders…
We want to establish an abbreviated, multidimensional, evidence based, diagnostic personalityprotocol within the mental health services. The hypothesis is that the mutidimensional testcombination of VTCI, NEO-FFI and CISS is sufficient reliable and…
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A constant Hb concentration will improve the quality of life of patiënts with a chronic need for bloodtransfusions.
Interferons (IFNs) are a family of cytokines which have important antiviral and antiproliferative properties. They also play an important role in immunomodulation. Type I IFNs have been implicated in autoimmune diseases, including systemic lupus…
A specific set of variables of impairments are related/ predictive of functional limitations and disabilities. A specific set of variables of functional limitations are related/ predictive of disabilities. Psychological variables (defined by TPB,…
The on-line intervention will prove to be significantly more effective in improving mood and reducing diabetes-related distress in diabetes patients with minor to moderately severe depression compared to the control condition (CAU, supplementend…
To evaluate the response to adalimumab treatment in TNF-alpha blockade naïve patients and patients who failed prior other anti-TNF-alpha treatment and to understand the mechanisms underlying the clinical response to TNF-alpha blockade.
1: Long term use of fluoxetine causes the excitability of the primary motor area of the brain to change 2: Long term administration of fluoxetine causes the muscle activation patterns to change
A proportion of patients with juvenile idiopathic arthritis with minimal disease activity can remain in a state of minimal disease activity with a lower dose of etanercept than the standard dose or even without etanercept.