3129 resultaten
Measurement of airways hyperresponsiveness by mannitol (Aridol©) as compared to methacholine saves time to the lung function technician, while being as sensitive to discern hyperresponsive from normo-responsive, and being at least equally acceptable…
Adherence to diabetes guideines is moderate, especially on educational aspects. Changes in lifestyle is a major element of the patient treatment. Studies on motivational Interviewing show promising results among dieticians. There are no primary care…
We hypothesise that accurate treatment of GOLD D patients in an integrated primary care system will improve patient outcomes over 12 months.
We hypothesize that systemic aPC will benefit patients with ALI/ARDS, as caused by inflammatory as well as infectious disorders, in terms of gas exchange, edema and capillary leak in these lungs, as well as in ventilator-days (duration of mechanical…
T-cell inhibition with Mycophenolate Mofetil (MMF) attenuates T-cell number, T-cell activation and T-cell – monocyte interaction, thereby minimizing the T-cell-driven inflammatory amplification loop. The latter will contribute to improvement of anti…
The aim of the pilot trial is to: 1. evaluate the potential effectiveness and effect size of the online self-management program for patients with Cardiovascular Risk 2. to identify outcome measures most likely to capture potential patient benefit…
Local corticosteroid injections combined with usual care will have a positive effect on experienced recovery and will reduce pain at 3 and 12 months follow up compared to usual care alone.
There is a clinically and statistically significant difference in the percentage of patients who achieve and maintain clinical remission (defined as DAS < 1.6) and in functional ability and progression of radiological joint damage after 1…
Multiproblem families (MPFs) provide a huge public health challenge because of socio-economic deprivation, psychosocial problems, parenting problems, domestic violence and rule-breaking behaviour. Therefore, there is a strong need for evidence-based…
Psychological factors (e.g. personality style) influence the course of CRPS-I but not the onset of this syndrome.
Does nurse-led follow up at home lead to improved quality of life an satifaction and a reduction of costs compared to medical follow up at the outpatient clinic, without compromising the medical condition of patients?
Ulcerative colitis is characterized by abnormal activation of the colon epithelium, which is considered to be a central pathogenic mechanism. Activation of colon epithelium cells in UC is associated with an abnormal high expression of Toll-like…
We hypothesize that e-health, consisting of internet guided monitoring and self management training online, for patients with atopic dermatitis combines cost savings with an improvement in quality of life.
Through stress the mast cells become activated and by their vaso-active substances the mucosa permeability will become increased. Therefore the mucosa is easier to penetrated by microbes and acid. This increased permeability will leads to…
Treatment of patients diagnosed with laryngeal cancer with total laryngectomy with or without (chemo)radiation often induces speech, swallowing and shoulder complaints. Speech, swallowing and shoulder exercises may prevent or diminish these…
In the process of developing a serious game for testing patients’ level of myocontrol a part of the test needs to be validated. This validation is the goal of the current study. The part of the test that needs to be validated focusses on the…
Rates of neuropsychiatric symptoms are extremely high in institutionalized people with young-onset dementia. Neuropsychiatric symptoms are associated with reduced quality of life of residents and higher caregiver burden. Therefore, the Grip care…
PolyEthylene Glycol with ascorbic acid (PEG-asc) bowel cleansing preparation could contribute to the development of low potassium values. Hypokalemia is partially a pre-existing matter before bowel cleansing. Elderly are at risk for development of…
This study examines the interplay between adolescents’ peer relations and molecular genetics in predicting risk behaviors. The central question is: How do molecular genetic information and peer dynamics interplay in explaining adolescent risk…
Cognitive behaviour therapy and Self-examination therapy are both more effective in reducing depressive complaints than a waiting list control group.