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Bone remodelling in femoral neck fractures treated with a dynamic hip screw.

We expect an increased bone mineral density in the calcar region compared to the other ROI’s. Furthermore, we expect early detection of decreased mineral density of the femoral head in patients developing osteonecrosis of the femoral head.

The use of audit and feedback to improve patient care and reduce practice variation in paediatric tonsil surgery

We hypothesize that providing feedback to hospitals will reduce practice variation

Blood-borne Assessment of Stromal activation in esophageAL adenocarcinoma to guide tocilizumab Therapy: a randomized phase II proof-of-concept study

Patients with ADAM12 > 203 ng/mL in their serum benefit from the addition of biweekly tocilizumab for 3 doses to neoadjuvant chemoradiation before esophagectomy

The Caring Universities Project

We anticipate that students who will receive the Internet-based intervention based on their symptoms will have high satisfaction and show high adherence to the program. We also expect to find significant improvements in symptoms of stress /mood and…

EDB for Ménière's disease

We hypothesize that the number of patients without vertigo spells at 12 months follow up will be higher in the group that has undergone EDB than in the decompression group.

Effectiveness of Standard Urotherapy in children and adolescents with DUI: A Randomized Controlled Trial (RCT).

SU results in a higher rate of self-initiated toileting and a decrease in urinary/faecal accidents.

An explorative and feasibility study of Venetoclax combined with Tamoxifen in patients with relapsed/refractory Diffuse Large B-cell Lymphoma

TAM and ven can be used with acceptable safety and there will be a measurable overall respons. Study is exploratory, so no numbers are given yet.

Needle arthroscopic meniscopexy

We hypothesize that compared to traditional in-OR surgical intervention, in-office, needle arthroscopic meniscopexy will be preferred by patients, decrease time-to-recovery and be less costly.

Captain Morgan Study

Compared to the Allis technique, the Captain Morgan technique is more effective in reduction of posterior dislocations of total hip prostheses using procedural sedation and anesthesia in the emergency room

Blood flow in glaucoma and tinnitus

The amino acids from the glaucoma patients will show a decrease in nitric oxide bioavailability and there will be an increase in excitotoxicity markers in those with tinnitus.

A randomized study on probiotics and their effect on vitamin K2 status

We hypothesize that probiotics with vitamin K2 producing properties can improve vitamin K status, which will eventually reduce the risk of coronary calcification.

Hypothalame serotonine transsporters in mensen verdacht voor hypothalame schade.

We hypothesize that subjects suffering from hypothalamic dysfunction may have a hyposerotonergic neurotransmission. Therefore we will investigate if there are differences in specific hypothalamic-to-nonspecific [123I]FP-CIT binding ratios using…

Standard versus high definition colonoscopy.

Assess of the effect of HD colonoscopy alone or when combined with different I-scan functions compared to standard colonoscopy with respect to adenoma detection rate.

Prediction of REsPonse to Antipsychotics using
electRoEncephalography

We expect that EEG characteristics can serve as predicite biomarker for treatment response in patients with a first psychotic episode.

Timing in premedication for upper endoscopy

The timing of administration of simethicone influences mucosal visibility during upper endoscopy

Opgroeien in Amsterdam

The primary aim of this study is to examine whether a parenting intervention that increases sensitive parenting improves children’s stress system functioning and reduces disruptive behavior, and to examine whether these improvements are causally…

Course of psychosocial problems of lungcancerpatients before, during and after treatment (chemotherapy).

N/A

Measuring the effectiveness and efficiency of a communication training for medical specialists focused on patients with medically unexplained physical symptoms (MUPS).

Training medical specialists in consultation skills focused on MUPS patients improves the specialistic care for these patients in terms of illness worries, course of symptoms and daily functioning and reduces the medical costs for this patient group…

EMDR Flash Forward as an intervention on the mental images of worst case scenarios in paranoid delusions

The preoccupation with the paranoid delusion decreases after intervention with EMDR Flash Forward

Diagnosis of pre-eclampsia.

What is the contribution of the serum markers sFlT-1 and PlGF in the diagnosis and management of pre-eclampsia.