337 resultaten
We aim to test the accuracy of Western gastroenterologists in differentiating T1 CRCs from its precursor lesions and subsequently in estimating invasion depth
The purpose of the study is to conduct a randomised controlled trial with the onlinecourse 'Voluit Leven' as an intervention to study the: 1. Cost-effectiveness in terms of reduction of psychological symptoms (mood symptoms and disorders…
We want to establish an abbreviated, multidimensional, evidence based, diagnostic personalityprotocol within the mental health services. The hypothesis is that the mutidimensional testcombination of VTCI, NEO-FFI and CISS is sufficient reliable and…
Interferons (IFNs) are a family of cytokines which have important antiviral and antiproliferative properties. They also play an important role in immunomodulation. Type I IFNs have been implicated in autoimmune diseases, including systemic lupus…
To determine the influence of the fatty beverage Cow’s milk on the systemic exposure (AUC) to erlotinib in patients with or without concomitant use of a PPI.
1) Molecular analysis of breath can be used to discriminate between patients that are suspected of ventilator-associated pneumonia (VAP) who have positive cultures and who have negative cultures with high sensitivity (which could limit antibiotic…
Glucose control by closed loop in diabetes type 1 is equal to glucose control by insulin pump.
The use of motivational counselling and inclusion of a written health plan in an occupational health examination will improve personal work resources and work ability at 12 months follow-up
Treatment of fear of falling in hip fracture patients in GR, using the FIT-HIP intervention, will lead to reduction of fear of falling and therefore to an improvement of mobility function (gait and balance), in comparison to patients with fear of…
1. Providing children with tailored non-smoking advice will prevent them from becoming a smoker; 2. Children receiving tailored non-smoking advice will have stronger cognitions in favour of non-smoking; 3. Prompting children through e-mail and SMS…
1. To assess the safety and tolerability of different doses of a single IV injection of OTL-038 2. To assess the efficacy of ascending doses of a single IV injection of OTL-038 in detecting ovarian, renal cell or endometrial cancer during surgery by…
1. The STERK-intervention will prevent early onset of anxiety and mood disorders in offspring (compared to a minimal information condition); 2. The STERK-intervention is cost-effective; 3. The effectiveness of the STERK-training will be influenced…
Xenon wil provide improved hemodynamics in patients undergoing cardioverter defribrillator implantation.
Rationale: There is no cure for dementia. Physical activity could be an alternative to medications in an effort to slow cognitive decline In healthy elderly subjects physical activity leads to improved cognition. Objective: Part 1: Main objective:…
It is increasingly recognized that the immune system is a major player in this obesity related disease and the switch from benign to malign (insulin resistance and DM2) obesity is associated with changes in the immune system . In this regard, animal…
1. Frequency of temper tantrums will decrease; 2. Duration of the temper tantrums will decrease; 3. Intensity of the temper tantrums will decrease.
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The primary goal of this study is to determine whether it is possible to discontinue treatment with TNF blocking therapy in patients suffering from Rheumatoid Arthritis when the patient has had stable low disease activity.