136 resultaten
Background: Injury rate and injury severity of elderly cyclists due to self-induced cycle accidents increase with age. Starting at the age of 55 years, injury risk increases with a factor 4 at the age of 75 years. Injury mechanisms such as slippery…
The combination of breast surgery, radiotherapy and chemotherapy have a profound effect on the deep myofascial level and in turn, they create a vicious circle of adhesions and lack of mobility and pain in muscles, fasciae and joints around the…
Combination therapy with telaprevir/ ribavirin is as effective as the current standard of care with peginterferon-alfa/ ribavirin for the treatment of acute Hepatitis C in HIV-infected individuals.
Our hypothesis is that custom made insoles and a home-based exercise program would be superior to a home-based exercise program alone at 12 weeks follow-up.
In adult congenital heart disease patients with exercise-induced pulmonary arterial hypertension, treatment with bosentan lowers the mean pulmonary arterial pressure, which may result in improvement of the cardiopulmonary circulation,…
The effectiveness of school-based ('Op Volle Kracht') and computerized ('SPARX') depression prevention programs will be tested in a Dutch sample of adolescent girls with elevated depressive symptoms. The programs will be tested…
Is a prevention program, based on principles of health behavior change, education about playing-related musculoskeletal disorders and postural training, more effective in preventing and/ or reducing disabilities from musculoskeletal complaints in…
The hypothesis is, when adolescents are screened for problems at an early stage and do get help, they will be less absent from school and will have less psychosocial problems.
The aim of the study is to compare the efficacy of per-oral endoscopic myotomy (POEM) to the efficacy of pneumodilation as the initial treatment of symptomatic idiopathic achalasia. It is hypothesized that POEM has a higher long-term efficacy than…
The primary objective of this study is to analyse whether preventive hamstring exercises (Nordic Hamstring Curl) can reduce injury incidence in Dutch elite amateur soccer players. The secondary objective of this study is to analyse whether…
In patients with side effects, during VNS, there is: 1. A decrease in lung function parameters; 2. A reduced increase in heart rate; 3. A reduced increase in blood pressure.
By introducing of PK-guided individualized dosing of pazopanib we hypothesize that the interpatient variability can be reduced by 50%.
Patients with subarachnoid hemorrhage (SAH) treated by standard, state-of-the-art SAH management with additional ultra-early and short-term TXA administration (TXA group) have significantly more often a favourable outcome after six months (score 0-3…
Een kortere gipsduur gaat gepaard met een betere functionele uitkomst.
To investigate whether the addition of preoperative radiochemotherapy to the standard treatment, consisting of explorative laparotomy, pancreaticoduodenectomy if possible, followed by adjuvant chemotherapy, improves the overall survival (analyzed by…
To demonstrate proof of principle for the elimination of malaria from Rusinga Island using the nation-wide adopted strategy of LLINs and case management augmented with mass trapping of mosquito vectors.
Recurrent miscarriages is defined as three or more consecutive miscarriages prior to the 20th week of gestation. Whenever the diagnosis ‘recurrent miscarriages’ is established, an underlying cause may be identified in about 25-50% of cases. A…
We hypothesize that more participants in the experimental condition, who are offered the computer-tailored feedback program, will quit smoking and that these participants will become more physically active compared to the participants in the control…
The incidence and types of infection are comparable in sterile suturing or clean suturing of traumatic wounds. Clean suturing is cheaper, less time consuming and requires less assistence that sterile suturing