342 resultaten
We aim to test the accuracy of Western gastroenterologists in differentiating T1 CRCs from its precursor lesions and subsequently in estimating invasion depth
We hypothesize that by using different imaging techniques, we can give a good characterization of the bone marrow microenvironment in advanced-stage myelofibrosis, before and during treatment with ruxolitinib.
H1: the exercise intervention is effective in reducing (work-related) fatigue H2: the exercise intervention is effective in improving (work-related) self-efficacy, sleep quality, work ability, cognitive functioning, and aerobic fitness.
Children aged 4 to 6 years in the intervention group who have received the GigaGaaf! intervention have a different oral health than children aged 4 to 6 years from the control group who have received care as usual. Parents of the children aged 4 to…
To determine the influence of the fatty beverage Cow’s milk on the systemic exposure (AUC) to erlotinib in patients with or without concomitant use of a PPI.
1) Molecular analysis of breath can be used to discriminate between patients that are suspected of ventilator-associated pneumonia (VAP) who have positive cultures and who have negative cultures with high sensitivity (which could limit antibiotic…
The use of motivational counselling and inclusion of a written health plan in an occupational health examination will improve personal work resources and work ability at 12 months follow-up
Treatment of fear of falling in hip fracture patients in GR, using the FIT-HIP intervention, will lead to reduction of fear of falling and therefore to an improvement of mobility function (gait and balance), in comparison to patients with fear of…
Informed consent procedures and information provision differs between different transplantation centers and transplantation professionals in The Netherlands. Donor knowledge and satisfaction may be influenced by the manner of information provision…
1. To assess the safety and tolerability of different doses of a single IV injection of OTL-038 2. To assess the efficacy of ascending doses of a single IV injection of OTL-038 in detecting ovarian, renal cell or endometrial cancer during surgery by…
There seems to be a biphasic process of bone mineral density (BMD) changes in osetoarthritis (OA). An increased bone mineral density (BMD) and a specific distribution of BMD in the cortical of the subchondral plates and below in the trabecular bone…
Rationale: There is no cure for dementia. Physical activity could be an alternative to medications in an effort to slow cognitive decline In healthy elderly subjects physical activity leads to improved cognition. Objective: Part 1: Main objective:…
It is increasingly recognized that the immune system is a major player in this obesity related disease and the switch from benign to malign (insulin resistance and DM2) obesity is associated with changes in the immune system . In this regard, animal…
We hypothesise endo/epicardial substrate homogenization in a first approach to be superior to endocardial substrate homogenization alone, in terms of recurrence on follow-up.
The hypotheses of this study are that parents at increased risk of parenting problems who receive the intervention Solid Parenting (“Stevig Ouderschap”) during the first 18 months after childbirth, will enhance their social support network and…
The use of a GDFT protocol during liver surgery instead of the widely used LCVP regimen has no influence on blood loss.
The phenotypical and functional capacities of lymph node derived lymphocytes correlate better with biopsy-proven acute rejection after kidney transplantation than peripheral blood derived cells.
The hypothesis of this study was that the Oxord UKA will not hamper the accuracy of the CT-based PSG for TKA during revision surgery to restore biomechanical limb alignment and prosthetic component positioning as calculated by the software and the…