590 resultaten
The following hypotheses will be examined: a. patients with multiple sclerosis who become cognitively impaired may experience an increase in pain experience (due to white matter lesions) b. hyperesthesia is known to be predictive of central…
This study aims to implement and evaluate an advance care planning (ACP) intervention for elderly nursing home patients with a limited life expectancy. The intervention consists of ACP discussions integrated with a structured multidisciplinary…
(1) Written imaginal exposure results in beneficial effects compared to no-intervention (2) Beneficial effects are greater for written imaginal exposure in the past tense than for written imaginal exposure in the present tense
The aim of this study is to determine a high level of agreement between readings obtained from the plasma levels and the Roche Accu-Chek Inform II.
A combination therapy (MDT and TESIs) is effective and cost-effective compared to usual care among herniated nucleus pulpos patients with an indication for a lumbar herniated disc surgery
Trends in and variability of vital signs reveal hidden information about the state and deterioration of the patient compared to absolute values of vital signs.
Infant formulae with higher levels of milk fat result in improved fatty acids absorption as compared to standard formula.
The hypothesis of the TRANSFORM II study is the non-inferiority of Sirolimus Coated Balloon versus Everolimus Eluting Stent in terms of Target Lesion Failure
The expectation of this study is that shorter duration of plaster cast immobilization is beneficial for the patients.
This is a superiority trial testing the hypothesis that analgesic ear drops as added to usual care (oral analgesics with/without antibiotics) provide superior ear pain relief over usual care in children aged 1 to 6 years with a GP-diagnosis of AOM…
1. The predictive biomarkers for tumor response to immuno modulating therapy will be a combination of adaptive and innate immune status per patient that will be estimated with a tumor biopsy before, 6 weeks after start treatment (optional) and at…
The primary objective of the present study is to investigate the effectiveness of the Resource Groups (RG) on patient outcomes compared to care as usual alone for people with severe mental illnesses. It is hypothesized that participation in the RG…
We hypothesize, that SCD patients ending with mixed mononuclear chimerism after non-myeloablative HSCT with alemtuzumab/TBI conditioning will preserve their immune response to vaccinations administered prior to the transplantation and will therefore…
A Community One Health approach (bringing human and animal health together at the community level) improves disease surveillance efforts by Community Health Workers, health knowledge and behavior and physical health in study populations.
The primary research questions are: 1. To what extent does a 4 week ReHab-TOAT regime lead to improvement of arm function in chronic stroke patients with either a severely or moderately affected arm-hand? 2. To what extent is any improvement of arm…
Feasibility and reliability of prehospital triage in patients with thoracic complaints/pain appropriate to a suspicious ACS
The WALK gait retraining program is more effective to treat patients with symptomatic mild to moderate knee OA and an extension deficit, compared to a standardised treatment protocol based on the KNGF (royal Dutch association of physiotherapists)…
The main objective is to investigate whether actigraphy can be used as an objective measure to designate the presence or severity of apathy in patients with schizophrenia. To this end, we will measure activity levels using an accelerometer (i.e.…
The overall hypothesis is that the developed exercise therapy program is feasible, safe and improves cardiorespiratory fitness, functional performance, reduces CV risk factors and disease activity in patients with RA and high CV risk.
We hypothesize that flexion induced by uterine contractions can be mimicked by manually performing a knee-to-chest flexion (KCF) leading to spinal flexion directly at birth while the infant is held in dorsoflexion in order to facilitate expulsion of…