47 resultaten
The aim of this study is to develop and validate an age-specific checklist that can help clinicians to identify elderly patients with personality disorders in need of highly specialized mental health care.
1.We expect participants in the experimental condition to show a reduced gmbling behaviour 2. We expect participants in the experimental condition to show a decrease in approach bias towards gambling cues, and weaker approach implicit associations…
1. We first propose that in advanced TC, not only tumor-associated macrophages (TAMs), but also circulating monocytes and bone marrow (BM) myeloid progenitors are functionally reprogrammed by tumor-derived metabolites even before their recruitment…
E-PsEYE in comparison with usual care is cost-effective.
Work package A The aim of work package A is to examine the effectiveness of analogy learning (based on implicit motor learning principles) compared to explicit motor learning on walking performance in people after stroke. Work package B The primary…
PPIs are prescribed very frequently and might cause potentially severe hypomagnesaemia. We carried out a study focussing on the prevalence of hypomagnesaemia in geriatric inpatients using PPI and evaluated risk factors contributing to this effect.…
We hypothesize that performing a total laparoscopic hysterectomy with same day discharge is safe and leads to equal levels of patient satisfaction when compared to admittance for 1 night.
This is an exploratory study to further delineate the microenvironment of the PT and (S)LNs in cervical cancer.
We hypothesize that the underlying mechanisms of the varying response in multiple parameters within an individual can be attributed to variability in the causal path between drug administration, drug tissue distribution, and tissue receptor…
In the Netherlands, 90% of the patients with gout are managed by general practitioners but most research has been done in secondary care. In primary care there are questions on the clinical relevance of long-term uric acid lowering treatment of gout…
1) Feasibility of EMDR in older adults (age 60+) is comparable to younger adults (age 20-60); 2) EMDR treatment of PTSD results in improvement of PDs and improvement of cognitive functioning. 3) Somatic and psychiatric comorbidity are negatively…
Primary Objective: Investigate the effect of modafinil (200 mg) and caffeine (300 mg) on vigilance in low, medium and high caffeine consumers during the circadian trough in order to determine: - To what extend vigilance during the circadian trough…
To evaluate the safety and feasibility of performing conservative surgery in women with stage IA2 or IB1 carcinoma of the cervix with favorable pathologic features
The reported incidence of delirium in the intensive care unit varies from 16 to 89%. A delirium is associated with increased mortality, increased hospital length of stay, higher cost of care and cognitive impairment. The Pain, Agitation and Delirium…
Cabozantinib improves overall survival in patients with hepatocellular carcinoma compared with placebo
The primary aim of the study is to evaluate whether the blended care intervention Living to the Full 55+ as an indicated prevention for anxiety complaints is more (cost-) effective than Treatment As Usual (TAU). We hypothesize that in comparison to…
In old age, sufficient protein intake is important to preserve muscle mass and function. Around 50% of older adults (65+ y) consumes ¡Ü1.0 g/kg adjusted body weight (BW)/day (d). There is no rapid method to screen for low protein intake in old age…
The results from this trial will provide evidence on whether structured risk assessments and customized maternity care for high-risk pregnant women by maternity care providers is feasible in terms of effectiveness, especially regarding maternal…