577 resultaten
Guanabenz is a safe and tolerable drug in young children en it ameliorates the disease course in patients with VWM
We hypothesize that transient inflammation/infection-associated deep venous thrombosis has a similar recurrence risk as 'classic' provoked deep venous thrombosis.
1. The level of adherence to the prostate cancer surveillance guideline will not differ significantly between GP-led and specialist-led survivorship care. 2. GP-led survivorship care will be more cost-effective than specialist-led survivorship care…
If there is a correlation between liking by smelling and liking by vaping, future experiments on e-liquid flavors would require smelling experiments only.
Infants’ growth when consuming hydrolysate-based formula is similar to growth when consuming a control formula with intact protein.
The literature indicates that a minimal endoxifen concentration of 16 nmol/L is needed to produce a therapeutic effect. This implies that the endoxifen levels in individual patients must stay above this threshold throughout the entire treatment…
Primary objective 1) To assess and compare overall QOL during each subsequent line and type of therapy. Secondary objectives: 2) To assess and compare therapy satisfaction / decision regret during each subsequent line and type of therapy. 3) To…
We hypothesize that the Think Cool Act Cool emotion regulation training is effective in improving emotion regulation skills and decreasing externalizing behavior problems, compared to care-as-usual. We also hypothesize that the training has a small…
Targeted Next Generation Sequencing (NGS) can distinguish benign pancreatic diseases, such as pancreatitis, from pancreatic malignancies during the diagnostic proces of patients with an uncertain diagnosis and treatment plan.
Recurrent respiratory tract infections (RTIs) affect 15-20% of children aged 0-5 years and cause high disease burden, frequent doctor visits and are one of the main reasons for hospital admission in childhood. Despite the common use of co-…
Phenylalanine supplementation can result in higher phenylalanine concentrations without causes tyrosine concentrations to rise too much
The Dutch version of the Breakthrough pain Assessment Tool (BAT) is a valid and reliable questionnaire to measure differences in breakthrough pain in patients with cancer
1. A frequency of two sessions per week is more effective than a frequency of one session per week. 2. Treatment type (EMDR vs.) ImRs moderates the frequency effect. 3. The frequency effect is mediated by memory, relationships and motivational…
The primary hypotheses of the study are: 1) High perceived daily stress, emotion dysregulation, and low mood at baseline predict higher drop-out, higher no-show, and poorer treatment outcome of Narrative Exposure Therapy (NET) (i.e., less PTSD…
1) To establish the prevalence and characteristics of dysphagia in hospitalized patients 2) To establish the relation between clinical dysphagia and sEMG characteristics
Music interventions will reduce anxiety and pain in patients undergoing a nuss bar procedure due to pectus excavatum
We expect to make recommendations in choosing between the PSFS or PSFS-D answering option and to describe important items from a patient's perspective regarding relevance, comprehensiveness and comprehensibility. We expect high correlation…
A personal health record (PHR)* is a practical, responsible and patient friendly tool to assist in the proces of recontacting in clinical genetics. * PGO in Dutch. In English I've used the term PHR or the broader term webapplication.
We expect that quality of life after nonoperative treatment is at least as good as after operative treatment.
It is possible to interrupt transmission of M. leprae in an endemic community by rigorous application of contact screening and chemoprophylaxis to both close contacts and a wider circle of contacts around each index patient. Post-exposure…