392 resultaten
Aim: to unravel underlying biomechanical and behavioural mechanisms of foot ulceration in a comprehensive load-capacity model, and design personalized interventions based on model outcomes. We hypothesise that: - Lower cumulative plantar tissue…
Our hypothesis is that growth hormone threatment in adults with Prader-Willi Syndrome will improve their metabolic and cardiovascuar health, thereby resulting in a reduced mortality.
Our hypothesis is, that this new type of fertility workup will have the same level of patient centeredness, with the benefits of less interference with their personal life and more discretion.
This will be a snapshot study, this is an hypotheses-generating design, without restraining to many in- or exclusion criteria. Thereby, this design generates a population-based overview, which rapidly provides insight in current clinical practice on…
Proximal serrated polyp detection rate is higher in endoscopists group who were trained by the e-learning.
Polystyrene sulfonate shows an in-vitro binding interaction with amitriptyline, causing 70-80% binding of amitriptyline to polystyrene sulfonate. The hypothesis is that polystyrene sulfonate binds to amitriptyline when taken simoultaneously in…
The aim of this study is to use Functional Respiratory Imaging (FRI) as a biomarker to get a deeper insight into regional changes in the distal bronchial and central bronchial airways of asthmatic patients on benralizumab treatment.
Stromal Vascular Fraction injection underneath burn scar will improve pliability of the scar more than fat grafting (historical cohort).
Primary Objective: Our first aim is to quantify dopaminergic function in mesolimbic/mesocortical dopaminergic pathways (measured with 18F-FE-PE2I PET) in PD-depression with or without anhedonia. We hypothesize that lower DAT-availability (i.e. more…
The hypothesis is that the slope of the curve will predict patient outcomes
The study population experiences difficulties understanding preventative COVID-19 measures and their mental health is negatively influenced by the COVID-19 crisis.
We expect differences in hedonic assessment of different e-liquid odors between the three groups, in a way that lkiking ratings for sweet e-liquid odors may be higher among non-smoking youth and young adults than smoking adults, and for non-sweet e-…
- The introduction of Robot assisted surgery leads to an initial decay in NTS behaviour during the learning curve of the team. - In experienced robot assisted surgery teams NTS behaviour is more explicitly expressed compared to experienced open…
HIIT improves motor and non-motor outcomes.
The timing of administration of simethicone influences mucosal visibility during upper endoscopy
The primary aim of this study is to examine whether a parenting intervention that increases sensitive parenting improves children’s stress system functioning and reduces disruptive behavior, and to examine whether these improvements are causally…
The degree of vulnerability (fragility) negatively impacts self-care, quality of life and their mutual influences in elderly patients with chronic heart failure, and the relationship with hospital (re) admission within one year.
We expect that EEG characteristics can serve as predicite biomarker for treatment response in patients with a first psychotic episode.
First we have to define its association with current objective inflammatory parameters and its quality to sense small (subclinical) changes in a short treatment period. If this quality exists, than the Handscan might be a new tool for objective and…
Pre-operative comprehensive digital Cardiac Counseling (prehabilitation) will reduce the cumalative incidence of MACE at 1 year postoperatively in patients operated for a cardiovascular procedure.