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1. Differences in usual care between rehabilitation centers lead to differences in functioning, patient satisfaction and costs 2. Community participation depends on various person- and disease-related variables.
We hypothesize that TRE improves insulin sensitivity, glucose values, and consequently neonatal and maternal outcomes in GDM, via strengthening of clock gene expression rhythms.
To determine whether the ‘Solomon laser-technique’, in which the entire vascular equator is coagulated, reduces the prevalence of TAPS or recurrence of TTTS when compared to the ‘selective laser-technique’, in which only the identifiable vascular…
The implementation of a bundel of pharamcological interventions aimed at stress reduction leads to lower pain scores and lower use of opioids in the PACU
Adalimumab is a more effecient drug than oral claritromycin alone in the treatment of hidradenitis suppurativa.
Stereotactic radiotherapy targeting a clearly defined electroanatomic arrhythmogenic substrate is effective and safe in patients with therapy-refractory VT
1. To investigate the intra- and interreliability of transperineal ultrasound measurements of the displacement of multiple points along the urethra in men after radical prostatectomy; 2. To compare the relative displacement of urethrovesical…
A threshold reduction in LDL-C is required to improve endothelial function as measured by the flow mediated dilation (FMD).
Anti-TNF treatment (infliximab (IFX), adalimumab (ADA)) has become standard therapy for refractory pediatric and adult Crohn¡¯s disease (CD) patients, and is used for the induction and maintenance of remission. When effective, clinical and…
This is an exploratory study, but we expect to find that the apparent diffusion coefficient on diffusion-weighted MRI and SUVmax on FDG-PET are able to differentiate between tumor tissue and treatment effects.
Patients administered perioperative reversed local infiltration of ropivacaine will have lower pain scores, a faster rehabilitation, and lower cumulative consumption of (opioid-) pain medication postoperative, when compared to patients administered…
A Wait and See-approach is non-inferior on percentage of patients in sinus rhythm at 1 month as compared to acute cardioversion, but leads to a higher quality of life and less costs.
It is hypothesized that this tailored intervention is effective in cancer patients with an adjustment disorder compared to a waitlist control group, and potentially cost-saving.
The expectation is that children with OBPL who received more physiotherapy have a better shoulder function than children with OBPL with less received physiotherapy.
We hypothesize that the employability intervention of 'Health & Motion', which consists of integrated care and a participative workplace intervention, will be cost-effective compared to usual care.
First randomization: The hypothesis to be tested is that the outcome in arm B (early intensification of rituximab combined with 2 weekly CHOP) is better than in arm A (no intensification of rituximab). Second randomization: The hypothesis to be…
It is expected that women who experience CIN as an urgent medical condition are more willing to use vaginal probiotics
We hypothesize that injecting an inert/biodegradable spacer between the dermis and the most superficial layer of the planned target volume (PTV) could remove the skin from the high dose volume, and this would result in a significant reduction of…