15218 resultaten
We postulate that exhaled breath sampling by an electronic nose can distinguish patients with rheumatoid arthritis with active disease defined by a disease activity score of 28 joints (DAS28) ≥ 3.2, from non-smoking asymptomatic controls.
Acute normovolemic hemodilution during coronary artery bypass surgery involving normothermic cardiopulmonary bypass (CPB) leads to dysfunction of cerebral autoregulation and therefore contributes to neurological morbidity after cardiac surgery.
The main aim is to evaluate the effectiveness of a blended behavioral activation intervention or the offering of psychological care using an e-health program blended with support offered by the mental health worker of the general practice (in Dutch…
The following hypothesis will be made: 1. P0 is the largest OS probability at 9 months which, if true, implies that the therapeutic activity of that regimen is too low. In the present trial, P0 has been taken as 35%; 2. P1 is the lowest OS…
It is expected that Covid-19 patients, whose symptoms are considered as "mild" (i.e., who have not usually been hospitalized) can experience prolonged complaints, resulting in reduced quality of life.
we hypothesize that paediatric patients with per-operative rhinovirus positive Polymerase Chain Reaction (PCR) testing have a longer paediatric intensive care unit (PICU) admission , compared to children who test negative.
The application of contrast-enhanced ultrasound can accelerate thrombolysis in patients with acute peripheral arterial occlusions.
Inhalation of a single regular dose steroid (200ugr Qvar autohaler) with a stretched upper airway (achieved by leaning forward and flexing the head backwards) will protect more against exercise induced asthma compared to inhalation of a single…
Nephrogeriatric assessment will be beneficial in identifying patients for whom conservative care might be a better option (QoL, clinical outcomes, costs) than starting dialysis.
We expect that the combined condition of open and structured will lead to the highest levels of participation, evaluation and the most optimal effects on intrinsic motivation and PA behavior.
To identfy the RP2D and preliminary estimate the efficacy, safety, and tolerability of the selected bosutinib dose and evaluate the PK in this patient population.
Patients with good outcome in terms of motor functioning and communication are likely to be discharged home without referral to further rehabilitation services. A substantial amount of these patients experience emotional and cognitive problems,…
Our hypothesis is that although treatment with etanercept improves the psoriasis and thereby the quality of lives in most people who are treated, in some people fatigue occurs as adverse event.
A short semi-structured assessment intervention (TA) results in immediate gains in terms of: 1. Clinical distress; 2. Hope/ demoralization; 3. Readiness for treatment (alliance, stage of change), as compared to a short action-oriented intervention…
The hypothesis is that the novel drug ARA290 is effective in alleviating neuropathic pain caused by small fiber neuropathy in sarcoidosis patients.
To validate the diagnostic performance of the electronic nose, the AeonoseTM, by analysing Volatile Organic Compounds (VOC) patterns in exhaled breath from patients with Mamma Carcinoma (BC) versus controls.
Better insight in the behavior of gastric banding surgery patients with use of determinants of the I Change Model (ICM), (knowledge, risk perception, attitude, social support, self-efficacy, intention and personality traits). Furthermore the…
H1: Compared to a control group of teams, employees in teams who are subject to the safety climate intervention will report higher levels of safety climate, -knowledge and -motivation measured at post-intervention (T1). H2: Compared to a control…