15233 resultaten
The use of PEG-asc could contribute a significant decrease in potassium values a potentially cause serious clinical adverse events.
The primary objective is to investigate the effectiveness of a personalized 2-year multidomain lifestyle intervention on cognitive performance in older adults at risk of cognitive decline.
helicopter transport can be done safe without changes in vital signs
We aim to use Epstein-Barr Virus (EBV) within nasopharyngeal carcinoma (NPC) tumour cells as therapeutic target. In these cells EBV “hides” in a latent state due to methylation of the viral promoters, expressing only few non-immunogenic viral…
Asthma patients experience more anxiety during COVID-19 compared to a stable timepoint in the past.
The hypothesis is that methylation marker panel, potentially combined with additional biomarkers, can predict (non-)regression of HGAIN, thus determining the need of immediate treatment versus active surveillance, and the safety of withholding…
The response on medical treatment for moderate to severe ulcerative colitis is visible on intestinal ultrasound within the first 6 weeks according to endoscopic response at 8-26 weeks
We hypothesize that ACT guided heparinization will result in a decrease of thrombo-embolic complications, without a significant increase in bleeding complications when compared to the use of a non-ACT guided standardized bolus of 5 000 IU. The…
Primary hypothesis: Capsular repair results in less postoperative pain 12 weeks after surgery compared to capsulotomy in patients undergoing hip arthroscopy. Secondary hypotheses: Capsular repair results in less postoperative pain at all other…
By introducing of PK-guided individualized dosing of pazopanib we hypothesize that the interpatient variability can be reduced by 50%.
1. Examine the reproducibility of the non-volitional endurance test in healthy subjects. The hypothesis is that the non-volitional endurance test is reproducible; 2. Comparison of muscle endurance tested at three different stimulation intensities.…
Sleep (quality and quantity) is beter in ICU patients when they are nursed in a single room compared to nursing in a 'open' ICU.
We hypothesize that the extended antibiotic prophylactic regimen is associated with increased infection-free survival of the implant within one year after revision arthroplasty (index revision arthroplasty) compared to a single dose.
The main endpoint will be successful sampling and storage of testicular tissue (that is 75% of the samples to be stored for future stem cell preservation will have germ cells). This can be identified based on histological analyses (immuno-),…
Transanal endoscopic microsurgery and extended EMR are both effective treatments for large rectal adenomas with comparable recurrence rates. However, EMR does not require general/spinal anesthesia or hospital admission and may be associated with…
Our hypothesis is that reverse arthroplasty has a better functional outcome and patient satisfaction than hemi-arthoplasty in patients with a three or four part proximal humerus fracture.
A. COMET as an additional transdiagnostic intervention focusing specifically on low self-esteem increases the effectiveness of mentalization based treatment in patients diagnosed with borderline personality disorder. B. This increased effectiveness…
"De Nieuwe Toekomst" will empower female victims of intimate partner violence by making them financial independent which reduces the risk of intimate partner violence victimisation
Information on the dynamics and shape of the device and how these change over time will improve our understanding about the fixation and/or sealing of the device, which may help in stent selection and in designing stent grafts that are more durable.