15233 resultaten
To determine the influence of optical quality on perimetry for phakic and pseudophakic healthy and glaucoma patients. To determine the influence of CLE on perimetry and optical quality for PAC patients.
The hypothesis addressed in this project is that serum calcification propensity is a predictor of coronary artery calcification progression.
The hypothesis states that the time tom complete an emergency airway with Cricath device is significant faster than with Quicktrach device, which will be studied on porcine cadaver models. In the second outcome, the hypothesis states that there is…
The hypothesis is that infants who receive the Infant Behavioral Assessment and Intervention Program (IBAIP) will be able to regulate themselves better and that disabilities will therefore be prevented or develop to a less serious degree.
This exploratory study will be a proof-of-concept, open-label, single-center study to explore the feasibility of anti-CD8 PET imaging to gain insights into the biodistribution of CD8+ T-cell before and after CD19-directed CAR T-cell therapy in R/R…
Our null hypothesis is that there are no differences in tibiofemoral joint kinematics after ACL reconstruction with LET and the tibiofemoral joint kinematics after ACL reconstruction without LET. Our alternative hypothesis is that ACL reconstruction…
There is no difference between patients managed with a decision aid compared to patients not managed with a decision aid, regarding the decision of conflict scale.
Postpartum urinary retention (PUR) is a complication with a varying prevalence, from 0.5 - 18%. For asymptomatic PUR, i.e. the ability to void but with a post residual volume (PVRV) of ≥150 ml, the estimation of prevalence is between 10-45%.…
We hypothesize that remote home monitoring can detect post-discharge complications early and might prevent hospital readmissions.
To investigate in an unselected memory clinic sample, the clinical value of 18F]FBB PET in terms of 1. change in diagnosis; 2. change in level of confidence of diagnosis; 3. impact on patient healthcare management.
Publishing a guideline is not enough. An implementation strategy is needed to improve pain reporting, pain measurement and adequate pain therapy.
Enzyme therapy with recombinant human alpha glucosidase results in prolonged survival; improvement or stabilisation of cardiac hypertrophy and function, improvement or stabilisation of pulmonary function and improvement or stabilisation of muscle…
We hypothesize that membrane-residing gangliosides are elevated in obese insulin resistant subjects and correlate to peripheral insulin resistance. Furthermore, we hypothesize that the perturbation of the insulin signaling cascade by elevated…
Current standard treatments for symptomatic benign thyroid nodules (SBTN) are surgery or radioactive iodine. However, these interventions pose a risk to an otherwise healthy person. Therefore, minimally invasive alternatives have been explored.…
Lapatinib inhibits the function of Cytochrome P450 3A isoforms and P glycoprotein.
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The main hypothesis is that a preventive self-help intervention based on ACT for adults with mild to moderate distress leads to a decrease in psychological distress (depression and anxiety), fatigue and an increase in psychological flexibility and…
Switching to sarilumab in patients with rehumatoid arthritis responding well to tocilizumab does not lead to a relevant increase in disease activity and is feasible with a persistence of sarilumab >70% at 6 months
The temporal artery biopsy has no additional value after a halo sign using ultrasound of the temporal artery