15233 resultaten
Continuous positive airway pressure on the deflated lung prevents total alveolar collapse, resulting in less local and systemic cytokine response, causing less pulmonary complications.
Thiopurine induced hepatotoxicity is related with an enhanced state of oxidative stress and may ameliorate after N-acetylcysteine supplementation.
This research project hypothesises that hyperoxic interval training improves whole body insulin resistance, endothelial dysfunction, cardiovascular fitness, lipid metabolism and glycemic control in the treatment of deconditioned non-insulin…
Sepsis is a major and growing problem. In the Netherlands alone, around 15.000 patients are diagnosed with severe sepsis each year. Despite major scientific efforts, including many failed clinical trials mainly focusing on inflammatory mediators and…
1. Adult subjects who are characterized by a high systemic inflammatory state as well as a high level of inflammation in adipose tissue will have the highest metabolic response to bariatric surgery, i.e. the greatest increase in insulin sensitivity…
The ingestion of free amino acids will result in higher plasma amino acid concentrations, resulting in enhanced muscle protein synthesis rates when compared with the ingestion of milk.
By developing a model which predicts the risk of bleeding with coumarin use, patients can be treated more effectively, potentially avoiding the need for specific antidotes. Besides decreasing the risk of bleeding (potentially resulting in less…
Infants on Peak Baby Premature will have a balanced growth (weight-height) in accordance with what can be considered normal for the target population (based on gestational age) and as shown by the use of specific growth charts and or local…
In this pilot study, which is a unique collaboration between UMCG and Prince Claus Conservatoire, we will obtain experience in performing live music for elderly patients after surgery and examining the effects on postoperative pain. Outcome will be…
This study aims to compare the immunological response to vaccination with HPV16 E6 and E7 synthetic long peptides with concomitant application of imiquimod at the vaccination site with vaccination without the concomitant application of imiquimod.
OTR4120 will improve healing of chronic ulcers.
Several studies have looked into hyperkalemia as adverse drug reaction of co-trimoxazole. Many of these previous studies have shown that co-trimoxazole induced hyperkalemia is a potentially dangerous adverse drug reaction, especially in high-risk…
We hypothesize that the combination of both the IPS and PA intervention is more effective than each of the interventions separately (IPS, or PA), i.e. ‘1+1 = 3’
Type 2 diabetes have altered chemosensitivity and are in fact sympathetically overactive compared to healthy controls during a hyperinsulinemic euglycemic clamp.
We propose that kinase activity profiling may be a potential clinical diagnostic tool to predict for tumor response to targeted therapy with tyrosine kinase inhibitors (TKI's).
Observational study
3D printed tailormade assistive aids may better fulfill the requirements and needs of clients with disabilities to support them in performing their activities of daily living than the currently available aids or handmade aids provided by…
1. Frequency of temper tantrums will decrease; 2. Duration of the temper tantrums will decrease; 3. Intensity of the temper tantrums will decrease.
We hypothesise that the new MRI protocol will be superior to the previous protocol at calculating lung volumes and central airways dimensions, and subsequently improve the detection and quantification of TA in both CF and asthma disease pathologies.
N/A