6329 resultaten
1. Is an early surgery treatment strategy in neurological intact patients, with rheumatoid arthritis and radiological signs of craniocervical pathology, (cost-) effective when compared to prolonged conservative treatment? What is the time-dependant…
To validate the Vancouver Symptom Score for Dysfunctional Elimination Syndrome in Dutch.
Survivors of sepsis are at high risk for the development of chronic kidney disease (CKD), cardiovascular events and mortality. Mitochondrial dysfunction, which mainly results from increased generation of free radicals, plays a key role in the…
The first hypothesis is that there is variation in the treatment and follow-up of IBD patients between providers and consequently in the outcomes of care. The second hypothesis is that the implementation of a uniform care pathway for the treatment…
We hypothesize that the epigenetic changes that are related to childhood trauma provide a treatment target for succesful treatment with SAMe of persistent depression in bipolar disorder
Early mobilisation, i.e. 6 hours after vascular closure after TF-AVI procedure, will maximize comfort, lower pain complaints, lower infection rate and raise overall patient wellbeing after TAVI-procedure without extreme increase in vascular…
Inhibition of CYP2D6 enzymes by SSRIs may lead to reduced endoxifen plasma concentrations and thereby possibly influence tamoxifen treatment outcome. Paroxetine is a potent CYP2D6 inhibitor and strongly reduces endoxifen plasma concentrations.…
The pharmacokinetics of a therapeutic dose of gemcitabine can be adequatly predicted from the pharmacokinetics of a microdose
1. What is the effect of information about tobacco additives for smokers and non-smokers? 2. Do participants visit and read all the information which is available on the website?
We test the hypothesis that guided self-help is not less effective and not more expensive than care-as-usual.
The objective of this project is to gain knowledge about the how and when of cognitive behavioral treatment (CBT) of Axis I anxiety disorders when there is co-morbidity of an Axis II cluster C personality disorder. It tries to answer the question…
We hypothesize that probiotics with vitamin K2 producing properties can improve vitamin K status.
About 15% of the patients with gallstones detected by EUS will pass the stones spontaneously into the bowel. This means that in these 15% unnecessary ERCP can be avoided.
The mission of the chronic ITP registry is to improve the knowledge of the treatment and course of patients with persistent of chronic ITP. The objective of the registry is to get more insight in the number of patients that need a treatment for…
A failure to signal the salience, and especially the anticipation of positive events, is thought to be at the core of social-emotional apathy (SEA) in patients with schizophrenia. This salience system is highly dependent on dopamine from the…
1) Early non-responders with MDD who after 5 sessions of CBT change from CBT to ACT will have fewer depressive symptoms by the end of therapy in comparison to early non-responders with MMD that continue CBT. 2) Early non-responders with MDD who…
We hypothesize that expiratory Volatile Organic Compounds analysis by an electronic nose is capable of discriminating between asymptomatic infants and infants with respiratory wheeze.