2090 resultaten
We hypothesize that penfluridol as compared to oral second generation neuroleptics (olanzapine and risperidone), will show better compliance (primary outcome) and therefore lower healthcare costs.
As EGFR plays a role in pathogenesis of both pulmonary arterial hypertension and systemic sclerosis, EGFR inhibition will lead to beneficial effects in disease course.
The aim of this study is to assess the predictive value of the HowRwe questionnaire in relation to the EUROPEP questionnaire by analyzing scores acquired in Dutch GP practices. We expect that high HowRwe scores are associated with an positive…
The primary hypothesis of this study is that Opsys will improve mild incontinence based on urine loss per 24 h measured by 24 h pad weight test (PWT). Primary Objective The primary objective of this study is to test the effectiveness of Opsys in a…
The study will investigate the effect of a synbiotic test product compared to a control product on the composition and metabolic activity of the gut microbiota of C-section delivered infants.
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Combined (repeated) laser photocoagulation prolongs time to failure compared to anti-VEGF monotherapy.
We hypothesize that the circulatory and cardiac effects of TEA will be most pronounced during circumstances of increased sympathicotonus, which will be induced by an exercise test on a bicycle.
Insulin detemir, when injected once daily at an individually appropriate time (either before breakfast or at bedtime), provides superior glycaemic control to insulin glargine injected indiscriminately at bedtime in patients that had clearly…
Does KiVa reduce the level of bullying and victimization in elementary schools?
To evaluate the effects of thoracic epidural anaesthesia (TEA) with general anaesthesia on mean systemic filling pressures, arterial- and venous resistance and cardiac output. To assess the hemodynamic effects of vasopressors and fluid loading under…
Treating a symptomatic urinary tract infection in patients with a long-term indwelling catheter for 5 days is non-inferior compared to the standard duration of 10 days of antibiotic therapy with regard to clinical cure rate.
Has a coach supervised intervention program targeting jump-landing technique effect on the incidence of lower extremity injuries.
The primary objective of this study is to determine whether treatment with Impella compared with IABP therapy after primary PCI reduces infarct size and results in a higher residual left ventricular ejection fraction in acute anterior wall…
We hypothesize that subjects taking propranolol (1h preoperative and directly postoperative) will report: 1. lower levels of state anxiety 2. lower levels of dental trait anxiety 3. lower levels of aversive traumatic memory 4. lower levels of…
Assuming that the use of SDD would result in an estimated infection prevalence of 25%, a difference larger than 10% was to be excluded, hypothesizing an equivalent efficacy of L. plantarum 299/299V plus fibre compared to that of SDD in preventing…
To detect any effect on disease-free survival from treatment with 3 neo-adjuvant and 3 adjuvant chemotherapy cycles (standard treatment) versus 6 neo-adjuvant chemotherapy cycles To study the effect of GM-CSF versus G-CSF on potential effect on…
The aim of the study is to assess whether in women with early PPROM tocolytics improve perinatal outcome.
Thoracic epidural anesthesia with local anesthetics produces intense sympathicolysis and protects the heart against ischemia during off pump coronary artery surgery
Objective of the study: The research aims to 2 new forms of treatment for patients with comorbid PTSD as a result of multiple and repeated abuse in childhood to assess and compare Imaginary Exposure. The expectation is that these new forms of…