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Immediate implant placement in molar extraction sites; a 5-year prospective case series pilot study

not applicable

A randomized phase II study of concomitant trastuzumab, bevacizumab with paclitaxel versus trastuzumab and bevacizumab followed by the combination of trastuzumab, bevacizumab and paclitaxel at progression as first-line treatment of patients with metastatic breast cancer with HER2-neu overexpression.

This study aims to establish if concomitant therapy of trastuzumab, bevacizumab with paclitaxel (regimen A) and/or trastuzumab and bevacizumab followed by the combination of trastuzumab, bevacizumab and paclitaxel at progression (regimen B) is…

Neoadjuvante chemoradiotherapie gevolgd door chirurgie versus actieve surveillance bij patiënten met een oesofaguscarcinoom

Active surveillance is non-inferior to surgery in patients with oesophageal cancer showing complete clinical response after neoadjuvant chemoradiotherapy.

Cord Clamping Study - Mpongwe (Zambia).

Anaemia is recognized as an important cause of morbidity and mortality in underfives. When associated with iron deficiency, anaemia may impair mental and motor development. There are indications that with iron therapy anaemic children fail to catch…

Patient Engagement Counter Cauti with an App

By providing patients reliable information and daily checklists via an app, we aim to give the patient a tool to be involved in the management of the catheter use. In this way, inappropriate use should be better signaled and discouraged, and the…

The prevention of lower extremity physical activity injuries; a school-based randomised controlled trial in children aged 10-12 years.

The promotion of safe sports participation proves effective in a physical education setting, resulting in a reduction of lower extremity injuries in children.

Effects of transfusion of leukocyte-depleted erythrocytes in cardiac valve surgery on postoperative complications.

To investigate the role and mechanisms of leukocytes in allogeneic erythrocyte concentrates on postoperative complications, as MODS, infections and death.

Strategies in early arthritis management.

After 2 years of treatment with a combination of antirheumatic drugs including adalimumab with the aim of achieving and maintaining remission in patients with mild arthritis, there is less radiographic progression than in patients treated with…

Effect of taste on sensory specific satiety.

The quality of taste affects sensory specific satiety. This is shown in both liking and wanting processes.

Study of the influence of singing in Dutch aphasia choirs on the speech and the quality of life of individuals with aphasia and/or apraxia of the speech.

An aphasia choir has been founded in our nursing home 2 years ago. The aim of the choir is to improve speech and language and to improve language skills of individuals who are suffering from aphasia and/or apraxia of speech. Some members of the…

Efficacy of Multi-Gyn LiquiGel for the relief of complaints related to vaginal dryness in post-menopausal women

Vaginal atrophy in post-menopausal women results in various vaginal complaints, including dryness. Multi-Gyn LiquiGel is a moisturizing gel with osmo-protectant ingredients. We hypothesize that LiquiGel relieves signs and symptoms of vaginal atrophy…

Evaluation of workflow improvements of new software solution to be used during coronary interventions

This evaluation does not have a hypothesis to be tested since it is intended to evaluate the workflow and usability of the new software solution, without prior defined performance criteria.

The effect of specialized nutritional intervention with a disease-specific sip feed (Cubitan) in the support of patients with pressure ulcers.

Improving the rate stage III/IV pressure ulcers heal through nutritional support.

Study on Cost-Effectiveness of Personality Disorder Treatment.

1. Effectsizes of the psychotherapeutic treatments vary between 0.5 and 2.0; 2. A lower dosage of psychotherapeutic treatment is mainly related to symptomatic improvement, while a higher a dosage is also related to structural and functional…

Refinement of rehabilitation strategies in patients with COPD.

Strength training followed by endurance + strength training is the most optimal training training regimen for depleted patients with COPD. Periodization of endurance and strength training is the most optimal for improving endurance in non-depleted…

Hand instruments are better accepted than rotary instrumentation for restoring tooth cavities in people with disabilities.

The ART approach is more suitable than conventional restorative treatment in people with disabilities

Prospective Assessment of Risk Factors for Appropriate ICD Intervention in Patients with Ischemic Cardiomyopathy.

The primary alternative hypothesis states that the mean relative infarct transmurality (RIT) is different in patients with (RITshock or ATP ) and without appropriate ICD intervention, i.e. shock or ATP.

Exploratory study to investigate the effects of a new infant formula in healthy term infants during the first 6 months of life.

That the combination of two known immunologically active ingredients can effectively modulate the intestinal microbiota and immune system and thereby might reduce the incidence of allergy and infections.

Corticosteroid injections in patients with trochanteric pain syndrome: open label randomized clinical trial in general practice.

Local corticosteroid injections combined with usual care will have a positive effect on experienced recovery and will reduce pain at 3 and 12 months follow up compared to usual care alone.

REspiratory Support in COPD after acUte Exacerbation.

Does chronic nocturnal ventilatory support at home after acute respiratory failure treated by (N)IV lead to a prolongation in time to readmission to hospital due to any following exacerbations in these patients compared to medical treatment only.