16235 resultaten
We hypothesise that aspirin 100mg at bedtime decreases tension by nocturnally lessening increase of the renin-angiotensin-aldosterone system, enhancing NO bioavailability, lessening autonomous nervous system activity or inhibiting COX-1 dependent…
The hypothesis is that children in the intervention group have better oral health (expressed in terms of caries) than children in the control group at the age of 48 (± 3) months.
The purpose of this study is to evaluate and compare the aesthetic definitive outcome of 1. Three different implant designs; and 2. Two different times of restoration, namely immediate and conventional restoration. The null hypothesis is that there…
Insulin detemir, when injected once daily at an individually appropriate time (either before breakfast or at bedtime), provides superior glycaemic control to insulin glargine injected indiscriminately at bedtime in patients that had clearly…
Is automated continuous monitoring of vital signs of patients on the surgical ward more effective than standard practice (= intermittent monitoring)?
patient preferences
1. Oral anticoagulant control is less stable at a low average intake of vitamin K; 2. As a consequence, a low dose vitamin K supplement results in a more stable anticoagulant effect in patients using vitamin K antagonists (VKA); 3. Dietary intake…
This study will test the effectiveness of Dragon in improving ADHD related symptoms, specifically in the areas of selective attention, impulsivity, hyperactivity/motor inhibition and motor skills in children with elevated ADHD-symptoms. It is…
We hypothesize that video-analyzed symptoms of dyspnea are a good predictor of the presence and severity of exercise-induced bronchoconstriction.
In this study we will test the effectivity of CBT vs. IPT in panic disorder with agoraphobia.
An unsupervised e-health supported neuromuscular training program, in addition to usual care in general practice, is more effective compared to usual care alone as a treatment for patients with acute lateral ankle sprains in general practice.
The primary objective is to investigate whether exogenous oxytocin administration enhances the placebo effect of classical conditioning and verbal suggestions as measured by subjective pain intensity to a previously validated heat pain conditioning…
Irregular heart rate can be detected with a camera-based monitoring technology.
Due to the ageing of the population, the number of (frail) elderly people who suffer from (multi)complex health complaints increases and this ultimately threatens their ability to function independently. Preventive home visitation programmes may…
Find the best predictive biomarker for respons to treatment.
Hypothesis: The implementation of microarray diagnostics is feasible in general practice in community hospitals.
Utilization of platelets stored in additive solutions has several advantages. A former RCT testing platelets stored in platelet additive solution II versus plasma excluded patients with factors of increased platelet consumption. In this study also…
The Prevention and Reactivation Care Programme uses an integral, multidisciplinary, and goal oriented approach that will lead to: 1. Early detection of elderly with an increased risk for loss of functional capacity during hospital stay; 2. Improved…
There is an increase in concentrations of cytokines IL-1alpha, IL-1RA and IL-8 (as measured using Sebutapes) in the skin of the arm in healthy volunteers after mechanical loading of the skin, compared with an control measurement.
Subgroup 1 (complex appendicitis without mass and/or abscess formation): LA is associated with reduced superficial site infections, shorter length of stay, less costs, less pain, and better hr-QoL, compared with OA without compromising overall…