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Randomised controlled trial of bed rest versus no bed rest, after intra-uterine insemination, impact on pregnancy rates.

Does a short time of immobilization (i.e. 15 minutes) after intra-uterine insemination have a potential advantage on pregnancy rates, compared to immediate mobilization and does it outweigh the disadvantage of the extra time and working space it…

(Dis-) advantages of the Wand.

Does the use of the Wand system reduces pain related behavior during the local anasthesia injection in children?

Ultraviolet related DNA-damage in skin of patients with atopic dermatitis and atopic status in relation to the use of Myfortic®.

The use of the oral immunosuppressant Myfortic® in the treatment of atopic dermatitis might be responsible for the delay the repair of DNA-damage in the skin after UV-exposition.

Survivors at Risk: a Randomized Controlled Trial of primary prevention of complicated grief among first degree relatives of suicide victims.

A brief (four sesssions) nurse-led family focused intervention, based on cognitive behavioral therapy and psycho-education, offered between 3 and 6 months following the suicide prevent depressive and complicated grief symptoms at 13 months…

Identification of predictive factors in synovial samples for the clinical response to TNF-alpha blockade in rheumatoid arthritis.

Can predictors of reponse to anti-TNF therapy be identified by immunohistochemical analysis of synovial tissue obtained before initiation of treatment?

Cryo strip versus classic strip of the great saphenous vein.

Recurrence rate of cryo strip is the same as classic strip of the great saphenous vein.

Effect of simvastatin on endothelial dysfunction, fibrinolysis, coagulation and inflammation after aneurysmal subarachnoid hemorrhage.

In patients with aneurysmal subarachnoid hemorrhage simvastatin restores endothelial cell damage, activates fibrinolysis, and improves coagulation and inflammation after the hemorrhage.

Intermittent Fasting and Insulin Sensitivity

In

Lean Healthy Male Subjects.

We hypothesize that peripheral insulin sensitivity increases after a period of intermittent fasting because of an increased turnover of IMCL and/or subsequent changes in the composition of intramyocellular lipids (glyco(shpingo)lipids and…

Pulmonary Inflammation during Mechanical Ventilation of Patients with Healthy Lungs.

It is hypothesized that mechanical ventilation using lower tidal volumes and PEEP causes less local inflammation in patients with healthy lungs than mechanical ventilation using traditional tidal volumes and no PEEP.

To boost amino acid oxidation in diabetes

Sodium phenylbutyrate administration in patients with T2D would improve whole body insulin sensitivity.

Distress and quality of life in autologous stem cell transplantation: stepped care.

Evaluation of the outcome of stepped care for psychological distress on functional status and other aspects of quality of life in patients with hematological malignancy treated with autologous stem cell transplantation following high-dose…

The use of SPEctroscopy during Endoscopy for Detection of PANcreatic Cancer

We hypothese that SFR spectroscopy is capable to distinguish benign and malignant pancreatic tissue by measuring wavelength dependent optical characteristics

The variations in small vascular function and arterial compliance during the menstrual cycle in young healthy women.

De microcirculatoire functie is cyclus afhankelijk bij gezonde ovulerende vrouwen.

A prospective double blind randomised controlled study to evaluate the immunological benefits and clinical effects of an elimination diet using an amino acid formula (AAF) with an added pre-probiotic blend in infants with Cow's Milk Allergy (CMA).

Development of oral tolerance to cow's milk at 12 months of treatment in infants with IgE mediated Cow's Milk Allergy (CMA) on control or test formula.

@home: a study to investigate the subjective and physiological efficacy and safety of Lybrido and Lybridos in the domestic setting in healthy female subjects with Female Sexual Dysfunction

In the present study we will investigate the efficacy of Lybrido and Lybridos in two subgroups of subjects with FSD in the laboratory and in the domestic setting of these subjects. We will measure subjective, physiological and neuropsychological…

A 6-thioguanine (6-TG) registry that explores the effectiveness and safety of 6-TG in the long-term treatment of inflammatory bowel disease (IBD).

Patients will remain in clinical remission after switch to Thiosix

Contact-based Intervention for Infants during Transition to Centre-based Care

1. Compared to the control group, 4 weeks and 8 weeks after the start of centre-based care infants in the intervention group will show: - Lower morning and afternoon levels of salivary cortisol - Less disruption of the gut microbiota and an improved…

Epidural versus intravenous analgesia in children; a double-blind randomized controlled trial.

To investigate whether epidural analgesia provides a better postoperative pain control than intravenous opioid analgesia in children and whether epidural analgesia is associated with reduced postoperative morbidity.

A relapse prevention programme for patients with (partially) remitted anxiety and depression: the GET READY study

The aim of this study is to implement and evaluate a guided self-help online relapse prevention programme for patients who are completely or partially in remission from anxiety and/or depressive disorders, and who previously received treatment in…

Preventive effects of Transmural Integrated Care ( TIC,"ketenzorg") on disabled persons within homes of the elderly.

Transmural integrated care is effective on quality of life, functional health and disability.