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Clinical, microbiological and radiographical evaluation of implant surface decontamination using air-polishing in the surgical treatment of peri-implantitis; a randomized controlled trial

No difference exists in clinical, microbiological and radiographical outcomes in the surgical treatment of peri-implantitis using air-polishing or handinstrumentation

Sinus pilonidalis (haarnestcyste in de bilspleet): fenolisatie (dichtbranden) vs. radical excisie (operatieve behandeling); een gerandomiseerde studie

The hypothesis of this study is that phenolisation of the sinus tract vs. primary surgical excision in patients with a symptomatic sacrococcygeal pilonidal sinus disease reduces days unable to do normal activities with only a small increase in…

Improving positive interaction between depressed mothers and their infants:
A effect study on a preventive program for mother mother and child.

The mother baby intervention positively affects the quality of the mother-child interaction, particularly the mother’s sensitivity towards her child and the child’s responsiveness and involvement, and (2) The intervention positively affects the…

Onderzoek naar de kosten-effectiviteit van het stoppen van bloeddrukverlagers en/of cholesterolverlagers bij patiënten met een laag risico op hart- en vaatziekten in de huisartsenpraktijk.

Guidelines in the field of primary prevention of cardiovascular disease (CVD) are regularly revised. The thresholds for recommendation of pharmacological treatment differ between the old and new guidelines. Re-evaluation of a patient's need for…

Enteral versus parenteral feeding in pediatric oncology patients with gastro-intestinal mucositis

Which of 2 feeding strategies for children during chemotherapy induced mucositis is optimal for the patient: an elementary diet, containing only simple macronutrients administered via continuous enteral drip; or total parenteral nutrition.

Rehabilitation after hip arthroscopy: comparison of two treatment strategies.

The aim of the study is to compare two physiotherapeutic rehabiliation strategies (supervised versus less supervised) in patients after hip arthroscopy for FAI and/or labral pathology. The hypothesis is that both groups will equally recover in the…

The effects of low dose 1,25-dihydroxyvitamin D3 on the polarising of cellular immune reactivity towards type 2 immunity.

Short term oral low dose 1,25(OH)2D3 in man will increase type-2 and decrease type-1 cellular immune reactivity without affecting serum calcium levels. Hereby, the potential usage of 1,25(OH)2D3 for immuno-therapeutical approaches will be…

Epidemiology of injuries, treatment (costs), and outcome in burn patients admitted to a hospital with or without dedicated Burn Center (BURN-Pro); a multicenter prospective observational study

The majority of patients admitted outside a dedicated Burn Center will have a maximum of 10% Total Body Surface Area burned.

A multi-centre, randomized, double-blind trial studying the effect of misoprostol on the outcome of intra-uterine insemination.

Pregnancy rate after insemination would be 50% higher after application of misoprostol.

Effects of Olanzapine standard oral tablets and orally disintegrating tablets on gut hormones, glucose metabolism and pituitary hormones.

Novel antipsychotic drugs cause weight gain and type 2 diabetes mellitus in a large percentage of patients. The mechanism of the serious metabolic side effects of these drugs is unclear. Olanzapine orally disintegrating tablet has been found to…

Use of vessel sealing system (ligasure) thyroid surgery: time saving? A prospective randomized study.

Use of a vessel sealing system (ligasure) in thyroid surgery reduces operation-time.

Burden of disease experienced by patients following a watch-and-wait policy for locally advanced rectal cancer: A qualitative study

In this study, we aim to identify Watch-and-Wait patients’ experiences and functional outcomes during their follow-up period and how the disease, its treatment, and the Watch-and-Wait program effects their daily life. Findings of this study can…

Preoperative risk estimation for onco-geriatric patients.

This study will be performed to test the predictive value of the GFI, the VES-13 and the timed “up and go” test compared to components of PACE in elderly patients of the age of 70 years and above undergoing surgery for a solid tumour.

A phase II, randomized, single-blind study to investigate the safety and efficacy of 3 dosing regimens of ABP-700 for procedural sedation in adult patients undergoing colonoscopy.

Phase I testing of ABP-700 alone and with remifentanil co-infusions have shown the ability to produce consistent dose dependent sedation effects with conditions favorable for procedural care including minimal involuntary muscle movement, stable…

Long-term effects of bariatric surgery.

N/A

A randomised study about the effect on survival of hormonal therapy versus hormonal therapy plus local external radiation therapy in patients with primary diagnosed metastasised (M+) prostate cancer.

Today the standard therapy for patients primary diagnosed with M+ prostate cancer (bone metastasis) is systemic hormonal therapy. If standard hormonal treatment will be combined with local external radiation therapy of the prostate the survival may…

Socio-economic predictors of formal dementia care with dementia

People from more disadvantaged backgrounds face barriers in accessing post-diagnostic dementia care.

The course of the mental health and quality of life of maltreated children.

N/A

A preference trial with rizatriptan 10 mg and ibuprofen 400 mg in migraine patients in the general practice.

Patients prefer rizatriptan over ibuprofen for the acute treatment of migraine.

Post operative pain treatment in orthopedic patients following a "Joint Care® " program for a total hip or knee replacement: an outcomes research.

1. Post operative pain treatment in orthopedic surgery in the Medical Center Alkmaar does not suffice; 2. Orthopedic patients undergoing total knee replacement use more morfine post OK than patients undergoing total hip replacement.