9127 resultaten
SNPs could increase systemic and CNS exposure, causing longer CNS PFS and less occurence of CNS metastasis
The hypothesis of this study is that a proactive strategy keeps the blood pressure at a safe margin and avoids dropping below the minimal acceptable threshold of a MAP of 65 mmHg. This proactive strategy may improve postoperative disability and…
1. That adherence to the WHO recommendations (2003) for early child feeding among low-income Quetzaltenango mothers, specifically adequate complementary feeding, is associated with higher growth attainment and greater disease resistance; 2. That a…
Multiple observational and animal studies suggest a therapeutic effect of bilirubin in various diseases. To verify this suggestion, intervention studies with experimental hyperbilirubinemia are needed. The current study explores the applicability of…
Systemic eosinophilic inflammation in airway disease (asthma/COPD/asthma-COPD-overlap-syndrome (ACOS)) is associated with small airway inflammation manifesting in dynamic hyperinflation and specific symptoms, which can be reduced by systemic anti-…
The FECAL trial, Fecal therapy to Eliminate Clostridium difficile Associated Longstanding diarrhoea.
Hypothesis: An important factor in recurrence of Clostridium difficile associated diarrhoea is persistent disturbance of intestinal flora. With restoration of flora by feces from a healthy donor future recurrences can be prevented.
• To determine if buprenorphine action at the MOR receptor can inhibit the respiratory depression response to IV fentanyl injection in healthy subjects and patients with chronic opioid use; • To determine if therapeutic concentrations achieved with…
Early antipyretic therapy reduces the risk of death or dependency in patients with acute stroke, even if they are normothermic
Fluorescent near-infrared imaging can accurately detect lymph nodes percutaneously and non-invasively during SLNP in melanoma patients.
Sinds een aantal jaar wordt de groepscursus ‘Ik Stop Ermee’ door een particuliere stichting op locaties in heel Nederland gegeven. De cursus bestaat uit één bijeenkomst van 4 uur en claimt een succespercentage van 70 tot 80% gestopte rokers na 1…
A better quality of life, function and energy expenditure within the rotationplasty patients compared to the patients with a above knee amputation.
Several reports on SED have shown the beneficial effects of CA supplementation on the down regulation of bile acid synthesis, increasing levels of primary bile acids and stimulating bile flow. Improvement in hepatic dysfunction, clinical improvement…
The AKITA® JET nebulizer is a new inhalation device with breath controlled inhalation. It regulates inspiration flow as well as inhalation volume, taking into account therapeutic requirements and the patient's individual condition. Doing so, it…
1. The incidence of falls in the elderly can be reduced by identifying elderly at high risk of falling followed by a systematic multidisciplinary examination of the causes of faling and by taking tindividual preventive measures (transmural health…
This is a normal healthy volunteer study designed to assess the safety and tolerability of bolus doses of ABP-700 in the presence of pre-medications commonly used in the monitored anesthesia care (MAC) setting.
It is hypothesized that patients who have no radiological evidence of disease after neo-adjuvant chemotherapy, have absence of malignancy on transurethral resection of visible lesions and scar tissue in the bladder just before radical cystectomy. In…
We hypothesize that MBM may have significant advantages over the ER-cap technique, especially in countries where endoscopic expertise is limited. The aim of this study was to assess the feasibility, safety and effectiveness of the MBM technique for…
We hypothesize that a six-week exercise program with the Balanseat according to the protocol contributes to therapy adherence and improves balance and gait in an elderly population.
People of South-Asian/Indian descent, such as the Hindostani population in The Hague, develop DM2 at a much younger age and lower BMI as compared to Caucasian controls of the same age and BMI. Moreover, the incidence and seriousness of…
Knee Joint Distraction in comparison with High Tibial Osteotomy in treatment of knee osteoarthritis.
Denuded bone areas are filled up with cartilage (determined with quantitative MRI) which is not anticipated to occur in case of HTO. The cartilage changes are compared two years post treatment.