9127 resultaten
It is expected that the experimental, but not the control participants, will show a significant decrease in depressive symptoms and anxiety, and a significant increase in physical activity, pro-social behavior and general mental health.
The DLBP is superior compared to the DHS in terms of revision surgery, union rate, avascular necrosis, implant related failure, as well as functional outcome.
motivational interviewing can be an effective method to support patients in maken lifestule behavior changes
To investigate whether a strategy of direct stenting without pre-dilatation is associated with a reduced incidence of restenosis at 9 month follow-up angiography, compared to conventional stenting with pre-dilatation or compared to a strategy of…
It is hypothesized that both caloric restriction and exercise lower tumor tissue protein synthesis rates but that exercise, as opposed to caloric restriction, will prevent a concomitant decline in muscle tissue protein synthesis rates.
The ADMA-level in hypertensive subjects will be reversely related to the basal blood flow and the endothelial NO-availability in the forearm. Pre-treatment with an angiotensin-II- receptorblocker and/or a statin will decrease the ADMA-levels via…
The main aims of the PROHTECT trial are to find out whether the compliance rate of the cervical screening programme can be improved by offering a self-sampling method for collecting cervicovaginal cell material at home for HPV testing, and…
Celecoxib, as a selective COX-2 inhibitor, has in vivo disease modifying activity in addition to its inflammation regulatory properties, in comparison to naproxen as a conventional non-selective NSAID.
A diagnostic strategy starting with bronchoscopic cryobiopsy is associated with a reduced need for chest tube drainage in comparison to a diagnostic strategy with immediate surgical lung biopsy, and is therefore associated with a lower patient- and…
Better symmetry corresponds with a higher satisfaction of the breasts
We hypothesise that in the Subacromial Pain Syndrome (SAPS), a differentiation between primary peripheral (i.e. (peri)articular) and secondary pain due to altered processing of pain, i.e. central pain sensitisation, is needed. We further hypothesise…
It is hypothesized that rituximab and abatacept are non-inferior alternatives to a second TNF alpha inhibiting therapy, for patients who have been adequately treated with a first TNF inhibiting therapy with insufficient effect.
Roux-en-Y Bariatric (RYGB) surgery is a successful approach to morbid obesity. In this procedure, the stomach is reduced to a small 'gastric pouch' . The duodenum is bypassed by connecting the jejunum this gastric pouch. The duodenum is…
The EMPOWER-GR RCT will test the hypothesis that a combined intervention of RET and protein supplementation with an oral nutritional supplement (ONS) is feasible in sarcopenic geriatric rehabilitation inpatients admitted after a hip fracture and…
Cardiovascular disease (CVD) is among the most frequent chronic diseases in the Netherlands. So, prevention is of high importance and primary care could play an important role. The cornerstone of CVD prevention is lifestyle change. However,…
Combined treatment (collaborative care + duloxetine) is more effective than mono-treatment (duloxetine or collaborative care + placebo) in depressive symptom reduction on the PHQ as main outcome for patients with MDD and (sub)chronic pain.
Metabolic disturbances associated with critical illness may disturb secretion of melatonin, the most important factor for circadian timekeeping. This disturbance may in turn hamper distribution and high quality sleep, with potentially detrimental…
Assuming that 80 % of the adolescents have a normal growth hormone secretion when retesting in puberty, we think there is no significant difference in final height between the group that discontinue growth hormone treatment (after a normal test in…
It is hypothesized that the lotteries will increase abstinence smoking rates over and above an effective smoking-cessation training program.