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Ibopamine 2% eyedrops in the treatment of patients with ocular hypotony after vitreoretinal surgery for retinal detachment or uveitis; Results after six months of treatment.

Long-term administration of Ibopamine hydrochloride eye drops restores and maintains intraocular pressure in patients with hypotony following vitreoretinal surgery for ablatio reinae, or uveitis.

Inducible Displacement in Total Knee Prostheses

TKR with large migration in the last 2 PO years show a larger inducible migration compared with TKR with little to no migration in the last 2 PO years

Efficacy of peripherally targeted inhaled rhDNase for persistent obstructive asthma in childhood.

rhDNase improves lung function in children with persistent asthma who have persistent obstructive pulmonary function; Treatment of mucus impaction is an interesting alternative approach to treat peripheral airflow limitation in asthmatic patients.…

Ziekenhuisopnames en/of overlijdensgevallen van Nederlandse reizigers eventueel gevolgd door repatriering: de HAZARD studie

To determine the frequency of the most common causes of hospitalizations abroad, repatriation or death of Dutch business and leisure travellers in recent years to identify risk groups for serious health problems.

Assessment of Perinatal Outcome with Sustained Tocolysis in Early Labour

Reduction of perinatal mortality and severe perinatal morbidity with sustained tocolysis with nifedipine

Adherence and patients’ experiences with oral anticancer agents.

The present study aims to get more insight into the use of oral anticancer agents in daily practice.

A feasibility study to test if an intervention can improve shared decision-making in advanced Parkinson's disease

The study will address the feasibility of the shared decision-making (SDM) intervention by (1) analysing the acceptability of the intervention by users (i.e. professionals and patients); (2) assessing the level of implementation; (3) testing…

Prevention of Migraine in Adolescents.

Based on systematic reviews concerning effective treatments in children with migraine a medical treatment (propanolol) as well as a non-medical treatment (relaxation therapy) appear to be effective compared to no treatment or placebo. however their…

Effectiveness of infliximab (TNF-alpha antagonist) in the treatment of late-onset depressive spectrum disorder in patients of 60 years and above.

Aetiology of late-onset depressive spectrum disorders may be different from the aetiology of early-onset depression. Concordant with the supposed aetiology of dementia, it has been postulated that chronic low grade immune activation plays a role in…

Pulsatile II study.

Pulsatile flow during cardiopulmonary bypass (CPB) results in preservation of microcirculatory function in the early postoperative period as compared to non-pulsatile CPB.

Treatment of PTSD in children

The present study aims at the improvement of the treatment of children with PTSD by examining the effectiveness of a brief intensive exposure therapy (IET) for children with PTSD using a multiple baseline design (patients are randomly assigned to…

Efficacy of probiotics and selective decontamination of the digestive tract in reducing bacterial translocation in patients with pylorus preserving pancreaticoduodenectomy.

Perioperative administration of probiotics or SDD has an effect on small bowel bacterial overgrowth and bacterial translocation to lymph nodes in patients undergoing PPPD by protecting or enhancing bowel (mucosa) permeability.

Cocaine en creativiteit

It is expected that acute challenges with cocaine will induce two opposing effect on creativity. That is, cocaine will increase mood leading to enhancement in divergent but not in convergent thinking.

Quality management: improvement of patient care in recently diagnosed rheumatoid arthritis.

It is possible to increase the efficacy of treatment in early RA-patients with MTX when treatment is intensified according to a strict and intensive, computer-assisted protocol. I.e. the number of patients in remission will increase.

Endometrial aspiration before or after Saline Infusion Sonography (SIS) in case of abnormal uterine bleeding; effect on specimen quality.

The specimen contains less evaluable endometrium after SIS than before SIS.

Circuit class training to improve the arm and hand function after stroke

Patients improve more in upper limb function after CCT in comparison to usual care. Patients are equally satisfied with both CCT and usual care as therapy. Patients have more active minutes during CCT in comparison to usual care.

Study to investigate the nutritional efficacy and suitability of infant formulae in healthy full-term infants.

The investigational formulae are equivalent to the currently marketed control formula with regard to weight gain of healthy full-term infants during first 16 weeks of life.

Effects of Per-Operative fluid Restriction in patients undergoing pancreatic surgery.

Our hypothesis is that peroperative fluid restriction will lead to a significant reduction of solid phase gastric emptying time ¨C measured by radionuclide scintigraphy-, and a reduction in its related postoperative complications.

The direct effects of NSAIDS on osteoarthritic knee cartilage.

Selective COX-2 inhibition is beneficial for matrix turnover.

Is hypnotherapy a valueble treatment for children with chronic abdominal pain?

Hypnotherapy is a valueble treatment for children with chronic abdominal pain.