17983 resultaten
Exploring QOL, hope, treatment motivition, coping en locus of control of patients considering early clinical cancer trial participation.
Based on literature we assume a 20% day 30 mortality of patients admitted to the hospital ward with COVID-19. We aim to lower this day 30 mortality to 10%.
Is there a diiference in antidepressant efficacy between ECT and a combination of ECT and nortriptyline? Does combination therapy with ECT and nortriptyline result in a faster antidepressant response compared with ECT monotherapy? Does combination…
The procoagulant state seen in patients with hiv can be a result of the immune activation due to the hiv infection itself or combination antiretroviral therapy (cART). In case the acquired thrombophilia is a result of immune activation, the…
we hypothesize that thermal comfort and sensation will stay within similar ranges in both conditions (based on a previous study);
Tacrolimus (FK506) is the main immunosuppressant that is prescribed after kidney transplantation. One of the disadvantages of Tacrolimus is the small therapeutic window. In transplantation patients therapeutic drug monitoring is routinely performed…
Knowledge generated by this study can contribute to the development of an approach to perinatal health inequities that can be implemented in all municipalities in the Netherlands, regardless of their size, location, and previous experience with…
1. Inhaltion of tobramycin containing aerosols using the INeb® in the TBM mode is less effective as inhalation of in the TIM mode; 2. The amount of deposition is correlated to the systemic Area Under the Curve of tobramycin after inhaltion of…
Comparison of progression free survival (PFS) in elderly patients with advanced CRC treated first line by tegafur-uracil plus LV or capecitabine. It is considered that, in this patient population, only differences in the median time to progression…
The intention to change behavior is related to changes in multiple physiological variables. Thermal comfort and thermal sensation are related to these physiological parameters. Furthermore, the intention of behavior is related to changes in thermal…
Point of care testing with Fcal POCT will reduce substantial the referral rate of children with chronic GI symptoms to the paediatrician.
Nebulised DNase has a decreasing effect on the duration of a hospital admission in infants admitted with an RSV-bronchiolitis.
Efficacy of inhaled DNase in children with an airway malacia and a lowerrespiratory tract infection.
We hypothesize that DNase improves mucociliary clearance and mucus retention in patients with (trachea)bronchomalacia during a lower respiratory tract infection, resulting in a faster resolution of symptoms and shorter duration of a lower…
Lateral eyelid block excision is not inferior to lateral tarsal strip procedure.
Treatment retention of crack cocaine dependent patients increases when a pharmacological agent is added to standard outpatient psychosocial treatment.
Early surgical treatment (exploration followed by resection (pancreatoduodenectomy or bypass) in patients with obstructive jaundice due to a pancreatic head tumor is equivalent in terms of severe complications of treatment compared with patients who…
In patient with clinically suspected appendicitis, imaging is needed to substantiate the clinical diagnosis. Imaging accuracy of US and CT is suboptimal, and the associated use of ionizing radiation and iodinated contrast medium are major drawbacks…
Therapeutic drug monitoring is effective in optimizing treatment with tobramycin and reduces side effects.
Decision aid will increase patient knowledge and reduce decisional conflict compared to usual care
The hypothesis is that the Manometric brace is superior to conventional plaster braces in terms of patient satisfaction, compliance and patient preference. For pain and hand function, no superior outcomes are expected for the Manometric brace…