407 resultaten
The purpose of the study is to conduct a randomised controlled trial with the onlinecourse 'Voluit Leven' as an intervention to study the: 1. Cost-effectiveness in terms of reduction of psychological symptoms (mood symptoms and disorders…
We want to establish an abbreviated, multidimensional, evidence based, diagnostic personalityprotocol within the mental health services. The hypothesis is that the mutidimensional testcombination of VTCI, NEO-FFI and CISS is sufficient reliable and…
Interferons (IFNs) are a family of cytokines which have important antiviral and antiproliferative properties. They also play an important role in immunomodulation. Type I IFNs have been implicated in autoimmune diseases, including systemic lupus…
Glucose control by closed loop in diabetes type 1 is equal to glucose control by insulin pump.
1. Providing children with tailored non-smoking advice will prevent them from becoming a smoker; 2. Children receiving tailored non-smoking advice will have stronger cognitions in favour of non-smoking; 3. Prompting children through e-mail and SMS…
1. The STERK-intervention will prevent early onset of anxiety and mood disorders in offspring (compared to a minimal information condition); 2. The STERK-intervention is cost-effective; 3. The effectiveness of the STERK-training will be influenced…
Xenon wil provide improved hemodynamics in patients undergoing cardioverter defribrillator implantation.
1. Frequency of temper tantrums will decrease; 2. Duration of the temper tantrums will decrease; 3. Intensity of the temper tantrums will decrease.
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The primary goal of this study is to determine whether it is possible to discontinue treatment with TNF blocking therapy in patients suffering from Rheumatoid Arthritis when the patient has had stable low disease activity.
In the present proposal we aim to study whether the intrauterine application of hyaloronic acid (Hyalobarrier ® Gel Endo) immediately after curettage, in patients with a recurrent curettage reduces the incidence and severity (ESGE score/…
1. Participation in an early home-based education programme compared to care as usual will significantly increase knowledge on kidney disease and treatment options, communication on renal replacement options and promote a positive attitude towards…
Increased cardiac sympathetic activity is highly prevalent among patienst with chronic heart failure. The increased cardiac sympathetic activity as assessed with 123I-metaiodobenzylguanidine (MIBG) is a usefull tool to discriminate responders (i.e.…
The hypothesis is: Using a multifaceted strategy, the implementation of recommandations will be more succesfull than by using a single strategy. The implemented recommandations will prevent hand eczema among health care workers.
The aim of this study is to provide evidence based dosing guidelines for vincristine in combination with azoles. Therefore we will study the pharmacokinetics of vincristine with and without concomitant azole therapy in pediatric patients with acute…
It is safe to withhold intravenous broad-spectrum antibiotics in low-risk pediatric cancer patients and to shorten antibiotic treatment in a subgroup of medium-risk pediatric cancer patients presenting with febrile neutropenia.
Isomaltulose reduces the decline in working memory and attention span in older children. This reduction in decline is also seen when lower amounts of isomaltulose are combined with a mix of minerals and vitamins.
1. Volume intervention by a diuretic and moderate sodium diet potentiates the antiproteinuric effects of aliskiren in patients with residual albuminuria during conventional RAAS-blockade; 2. Aliskiren neutralizes the reactive rise in plasma renin…
We aim to use Epstein-Barr Virus (EBV) within nasopharyngeal carcinoma (NPC) tumour cells as therapeutic target. In these cells EBV “hides” in a latent state due to methylation of the viral promoters, expressing only few non-immunogenic viral…