135 resultaten
We hypothesize that Moroccan-Dutch differ from native-Dutch in stress reactivity. This difference is not explained by group differences in known non-social risk factors for psychosis. Affirmative findings in the current study would support to the…
Employees in the health care service are at high risk to develop common mental health complaints. These can negatively affect work functioning, with possible serious consequences for the quality of care. It is crucial to keep health care workers…
AN-PEP helps to digest gluten in vivo.
The objectives are firstly that the Tackling Teenage training increases knowledge, skills and confidence of young people with autism spectrum problems (ASP) , and that inappropriate sexual behavior decreases and secondly that the (sexual)…
Artificial dynamic lightening can positively influence the sleep/wake cycle and reduce the disturbance of the circadian rhythm due to hospitalization.
We hypothesize that addition of low-dose haloperidol prophylaxis (1.0mg twice-daily) on top of the existing standard of care reduces in-hospital delirium incidence, severity and duration in a general patient population, age 70 years or over, who are…
To evaluate the impact of three different implementation strategies for implementing IBSM in current clinical practice, we have proposed the following three hypotheses: 1. Hypothesis 1 (Reach): More general practices will participate in IBSM in the…
Which of two strategies for early detection of depression in primary care performs best, i.e. results in higher number of identified depressions. The two strategies are: 1. Active case finding of high risk patients by a nurse practitioner; 2.…
The primary objective is to compare the pharmacokinetic profile of tacrolimus after rectal and sublingual administration with oral administration.
The addition of a Functional Capacity Evaluation to a cognitive behavioral intervention will improve work ability, quality of life and self efficacy.
1. Muscle ultrasound is capable to detect dermatomyositis and polymyositis in suspected patients; 2. Muscle ultrasound is capable to detect improvement of structural muscle changes induced by treatment; 3. Muscle ultrasound is capable to detect…
1. Describe concomittant electrical activation of endocardial and epicardial layers of atrium that have been shown in animal models to be dissociated, and to be involved in the perpetuation of AF; 2. Describe with a density mapping catheter the…
The implementation of the delirium part of the Vulnerable elderly project will improve when nurses have completed an e-learning tool regarding delirium care for elderly patients.
A levonorgestrel releasing intrauterine system (LNG-IUS) and endometrial ablation are two frequently used methods for the treatment of menorrhagia, of which the first can be applied by a general practitioner or a gynaecologist, whereas the second is…
Nowadays after every venous treatment some form of compressive treatment is prescribed. Its use has been proven for surgical interventions, but is unclear for EVLT. Patients often think of wearing of these stockings as a burden.Therefore we will…
Cancer is a common disease with serious consequences for patient’s physical and psychosocial functioning. These consequences may last for a long time, even after completion of the curative treatment. To overcome cancer-related problems and to…
We expect that, compared to the usual care, the complexity of care needs and the level of frailty of the elderly will diminish, wellbeing will increase, overall health care costs will decrease or at least remain equal and that quality of care will…
In this study, we build upon previous results and we aim to test whether the combination of cabazitaxel with repeated Rhenium-188 HEDP is feasible and leads to better PFS, OS and pain control compared to cabazitaxel alone in patients with mCRPC…
Prevention of progressive renal function loss remains the main challenge in clinical nephrology. Blockade of the rennin-angiontensin-aldosterone system (RAAS), which can be potentiated by a low sodium diet, is the therapy of choice, but still many…
To study the safety of co-infusion of a T-/CD19 B-cell depleted haematopoietic stem cells from haplo-identical donor and a single unit cord blood unit and to investigate the anti-tumor responses from both grafts.