2067 resultaten
Sex differences in renal physiology is a vastly understudied area, despite known differences in sex-specific rates of chronic kidney disease. Renal function decline is accelerated in men compared to women, suggesting a potential harmful role for…
From survey studies it is suggested that patient preference and satisfaction will be in favour of oral JAK inhibitors over parenteral biologics. 5,6,7 We want to establish the treatment preference of patients with active RA and compare the treatment…
The analysis of protease activity from saliva and the salivary biofilm, using these substrates, may provide a new layer of information useful in the discovery of prognostic markers with respect and related to the histopathological features of oral…
We aim to compare the accuracy of ultrasound derived blood flow parameters from the carotid artery to pulse-contour derived cardiac output and non-invasive cardiac output measurements. Our motivation is to develop a non-invasive, radiation-free,…
We hypothesize that the UC Diet (UCD) can improve induction of remission rates when administered with a 5ASA regimen to pediatric patients with mild-moderate UC vs. 5ASA regimen alone.
Study Hypotheses: We hypothesize that there will be: 1) High ratings of treatment acceptability (treatment satisfaction ratings) from participants 2) A reduction in depression (PHQ-9) and anxiety (GAD-7) symptoms, and perceived stress (PSS) scores…
Compare the gametocytocidal and transmission reducing activity of artemether-lumefantrine (AL) with and without a single dose of 0.25mg/kg primaquine (PQ) and sulfadoxine-pyrimethamine with amodiaquine (SPAQ) with and without single dose of 1.66mg/…
Most patients undergoing spine surgery with pedicle screw instrumentation will experience insufficient pain relief in the first three days after surgery, whereafter postoperative pain can be managed with conventional, non-opioid analgesics in most…
The monitoring performance of a wireless alternative for cardiorespiratory monitoring in neonates is equivalent (non-inferior) compared to routine monitoring with adhesive electrodes.
Diaphragm excursion measured from the PLAPS point is more feasible than from the subcostal view and yields comparable results of excursion
We hypothesize that it is feasible and safe to test the proposed FLOT-CROSS in a planned future phase III trial, defined as a success rate or at least 40% (success defined as completion of all four FLOT chemotherapy cycles and all CROSS CRT sessions…
Based on previous studies, we will expect that ambroxol improves neurological manifestations in patients with GD3.
We hypothesize there is a difference in CPM between the protocols
We hypothesize that PARP inhibitors can potentiate radiation-induced tumor cell death in patients treated with PRRT. To determine the maximin tolerated dose (MTD) of this combination, a phase 1 dose-escalation study is needed.
• There is no difference in number of bonding failures between the direct and indirect bracket bonding methods • Patients favour indirect bracket bonding over direct bracket bonding • Brackets bonded with the indirect bracket bonding will have less…
Short hydration during cisplatin chemo radiation is significantly more effective than long hydration in preventing acute kidney injury
The aim of this study is to evaluate the effects of platelet transfusions on hemostatic parameters in thrombocytopenic hematology patients and to identify other determinants of hemostasis, which may contribute to clot formation and clot strength.
We hypothesize that there will be a significant difference in anterior translation of the humeral head between patients and healthy objects. Secondly we hypothesize that the inter- and intra-rater reliability of the HHC test will be fair to good.…
Effectivity of information transfer between ambulance personnel and hospital staff (% content using SBAR system) Efficiency of information transfer between ambulance personnel and hospital staff (time)
The hypothesis is that testosterone supplementation improves functional mobility, quality of life, body composition, cognitive function, aortic stiffness and cardiovascular risk factors, and bone mineral density compared to placebo.