4117 resultaten
ARA290 will reduce disease activity in rheumatoid arthritis.
Xenon wil provide improved hemodynamics in patients undergoing cardioverter defribrillator implantation.
To assess the impact of the physical form of five different cocoa matrices on the bioavailability of the monomeric flavan-3-ols.
We propose that kinase activity profiling may be a potential clinical diagnostic tool to predict for tumor response to targeted therapy with tyrosine kinase inhibitors (TKI's).
1. Frequency of temper tantrums will decrease; 2. Duration of the temper tantrums will decrease; 3. Intensity of the temper tantrums will decrease.
The pharmacotherapeutic treatment of patients with cancer is generally associated with multiple side-effects. The cause of the side-effects is usually due to the toxicity of the drugs themselves. In addition, drug interactions can intensify side-…
Rationale: There is increasing evidence that Nicotine Replacement Therapy (NRT) may help adolescents to successfully quit smoking. However data on the effectiveness and safety of NRT among adolescents are limited and a large clinical trial of…
Inhibition of VEGF with Bevacizumab may have beneficial of deleterious effects on normal rectal microvasculature long time after radiation.
The hypothesis to be tested is that arm B is tolerable and that the outcome in arm B is better than in arm A.
Chronic chilblains is a common disease causing major restrictions in daily life, nevertheless little is known about treatment. In a literature search, we found thin evidence of three interventions: fluocinolone cream, nifedipine and vitamin D3.…
There are significant differences in the quantitative data for the groups of normally sigthed and visually impaired children older than 6 years. The hypothese is that is also for children from 2 until 6 years.
The purpose of the study is to conduct a randomised controlled trial with the onlinecourse 'Voluit Leven' as an intervention to study the: 1. (Cost)effectiveness in terms of reduction of psychological symptoms (mood symptoms and disorders…
Nebulizing amoxicillin clavulanic acid is more effective for reaching amoxicillin levels in sputum > MIC90 than amoxicillin clavulanic acid given by oral or intravenous administration.
We hypothesize that Moroccan-Dutch differ from native-Dutch in stress reactivity. This difference is not explained by group differences in known non-social risk factors for psychosis. Affirmative findings in the current study would support to the…
Stroke patients frequently complain of excessive fatigue, both in post-acute and in the chronic stage of their illness. The prevalence of severe fatigue is estimated between 28-73%, even in patients who seem to recover well. This may lead to…
We expect (in the intervention condition as opposed to the control condition): 1. A decrease in children's emotional/behavioral problems and rule-braking behavior; 2. An increase in children's on-task behavior; 3. An increased teacher…
Employees in the health care service are at high risk to develop common mental health complaints. These can negatively affect work functioning, with possible serious consequences for the quality of care. It is crucial to keep health care workers…
The addition of the EGFR monoclonal antibody Cetuximab to standaard concurrent chemoradiotherapy improves the outcome of treatment of locally advanced non-small lung carcinoma.
Time to recurrence of sustained VT (longer that 30 seconds or with hemodynamic instability) or VF with or without documented ICD therapy (shock or ATP) for VT of VF will be longer in patients randomized to substrate based ablation than in patients…
The hypothesis is that offering CBT in a group format while discontinuing antidepressant medication will reduce the high relapse rates in remitted anxiety disorder patients who discontinue pharmacological treatment.