4300 resultaten
We hypothesize that the epigenetic changes that are related to childhood trauma provide a treatment target for succesful treatment with SAMe of persistent depression in bipolar disorder
Victims of IPV, living in an unsafe and unhealthy situation, are faced with a broad range of physical and emotional symptoms. Standard and easy-accessible care to facilitate change into a safer situation is lacking. The project aims to launch an…
Early mobilisation, i.e. 6 hours after vascular closure after TF-AVI procedure, will maximize comfort, lower pain complaints, lower infection rate and raise overall patient wellbeing after TAVI-procedure without extreme increase in vascular…
The pharmacokinetics of a therapeutic dose of gemcitabine can be adequatly predicted from the pharmacokinetics of a microdose
This study will be an open observational study with the objective to test the feasibility of the mDLS. The variability of the methodology over time will be assessed. Blood flow and coagulation status assessed by mDLS and LSCI will be compared with…
Infant formulae with higher levels of milk fat result in improved fatty acids absorption as compared to standard formula.
The plasma concentrations of inflammatory mediators of AP subjects are similar to those of non-AP controls and elimination of the endodontic infection does not result in changes of the systemic inflammation. Finally ) to investigate the microbiome…
The aim of this study is to investigate an abridged version of an online health training, based on cognitive behavioral therapy components, that is focused on the optimization of health. It is expected that this online health training will have a…
Training for the HandbikeBattle and handbike training in general, will have a positive effect on physical health, physical fitness and quality of life in wheelchair dependent individuals.
To study if a Mediterranean diet (MD) followed by lean donor fecal microbiota transplantation (FMT) has synergistic superior beneficial effects on peripheral insulin sensitivity and (small) intestinal microbiota composition as compared to…
We hypothesize that a semi-rigid ankle brace especially designed for soccer players, wil reduce the incidence of ankle sprain injuries among amateur girls soccer players by 50%.
Vibrotactile feedback from a 'smart' fork reduces the eating rate of a teenage girl suffering from brain damage that causes her not to detect hunger or satiation
We hypothesize that in healthy individuals with Early-life stress (ELS), THC, which directly targets the endocannabinoid system, is more effective than hydrocortisone in improving stress adaptation and extinction learning in an experimental model of…
Inguinal hernia repair according to the TREPP technique results in less patients with chronic postoperative inguinal pain (CPIP) compared to Lichtenstein's technique.
Some smokers manage to quit completely by exclusively switching to e-cigs. However, some e-cig users tend to keep smoking their regular tobacco cigarettes (possibly less than before) in combination with their e-cig. The term “dual use” refers to…
We hypothesize that Network Pain Rehabilitation Limburg will be feasible in daily practice based on the found barriers and facillitators and perceived quality of care. Moreover, the effect of the different treatments on the physical functioning of…
Primary Objective: To gain insight in the disease mechanisms of IBD. Secondary Objective(s): To identify biomarkers and study functional and mechanistic properties of the mucosal immune system, gut and oral microbiome, epithelium, mucus barrier,…
This study aims to assess: - the efficacy of 9 cycles of ixazomib, daratumumab and low dose dexamethasone in newly diagnosed unfit and frail multiple myeloma patients. - the value of geriatric assessments to predict both feasibility and efficacy…