896 resultaten
The overall objective of this study is to assess safety of AG-348 and provide proof of concept of the efficacy of the drug in SCD patients. Based on currently available data, we hypothesize that the benefits of treatment of sickle cell disease…
Rationale: There is no cure for dementia. Physical activity could be an alternative to medications in an effort to slow cognitive decline In healthy elderly subjects physical activity leads to improved cognition. Objective: Part 1: Main objective:…
Stand-alone internet-based Vestibular Rehabilitation (VR) and internet-based VR with physiotherapeutic support is more (cost-)effective than usual care when treating dizziness in older patients in general practice.
It is increasingly recognized that the immune system is a major player in this obesity related disease and the switch from benign to malign (insulin resistance and DM2) obesity is associated with changes in the immune system . In this regard, animal…
In non-COVID-19 patients with pulmonary embolism a prevalence of up to 70% of concomitant symptomatic or asymptomatic deep venous thrombosis has been reported. Physicians experience an exceptionally high prevalence of pulmonary embolism in COVID-19…
Family Group Conferences will improve disability-management self-efficacy and participation in patients with amputation, acquired brain injury and spinal cord injury and their relatives
residual thyroid function is altered by short term oral antibiotic treatment in subclinical hypothyroid subjects as compared to healthy controls.
1. The primary objective of this study is to investigate whether nocebo effects on cowhage-evoked itch can be induced by verbal suggestion. We hypothesize that the verbal suggestion that the solution applied is an ‘itch solution’ will induce higher…
Patients with new-onset or recurrent AF have an altered myocardial sympathetic activity. The quantification of sympathetic activity with 123I-mIBG scintigraphy, as well as its change over time after restoration of sinus rhythm, can be used to target…
Observational study
It is expected that the use of the MFB intervention will improve subjective cognitive functioning.
descriptive study: data collection for norms of two novel infant assessments, i.e., the Infant Motor Profile (IMP) and the Standardized Infant NeuroDevelopmental Assessment (SINDA)
With this study we aim to disentangle mindfulness and placebo effects on pain. We investigate how decentering (a core component of mindfulness) and positive treatment expectations (a core component of placebo effects) interactively contribute to…
Similar or better fixation, migration and functional outcomes compared to other existing techniques
We hypothesise that the health behaviour of pregnant women is influenced by the measures to prevent the spread of COVID-19. It is not clear however, if it is positively affected (because of having more time, providing online options, creating a…
To determine the feasibility of the measurement protocol of a large prospective longitudinal study to describe the exercise capacity and physical functioning of critical illness survivors up to 5 years after discharge from the ICU.
Our hypothesis is that critical ill COVID-19 patients suffer more from their own immune response against the virus, than from the viral infection itself. Alkaline phosphatase (RESCAP®) has proven to reduce SIRS reactions by neutralizing the…
We expect the “movement with pain” program will result in a reduction in disability, improved perceived recovery, improvement of psychological wellbeing and increase in physical condition. Moreover, we expect that a combination of the amount of…
Environmental disturbances during ICU submission may explain observed EEG-arousals