6344 resultaten
Objective 1 to document the day by day changes of tinnitus that participants with intermittent tinnitus experience. Objective 2: to document whether the changes in tinnitus co-occur with changes in functional brain connectivity, and whether brain…
Adherence to the national guidelines is estimated at around 50%. Non-adherence does not lead to significant differences in clinical outcome such as readmission rate.
The introduction of a virtual asthma clinic may improve the number of asthma free days in children with asthma while the number of visits to the outpatient clinic is decreased by 50%.
Recent data showed for the first time that IgE-ACPA antibodies have a direct biological immune response in mast cells of IgE-ACPA+ RA patients. Subsequently, mast cell targeting agents, such as anti-IgE therapy have rationale for application in RA…
A decrease in HbA1c directly after the National Diabetes Challenge compared to baseline.
Muscular counterpulsation (MCP) is a new treatment option which seems to improve hemodynamics but might also have positive effects on muscular and vascular function. Additionally, it is non-invasive and does not seem to have relevant side effects.…
We expect that patient who receive care according to the protocol about 24/7 availability of specialized palliative care in the home situation, during the year of the study will die more often at home than patients in the years before start of the…
By sufficient electrical stimulation of the ampullary nerves, a congruent vestibulo-ocular reflex will occur.
Primary Objective: Our first aim is to quantify dopaminergic function in mesolimbic/mesocortical dopaminergic pathways (measured with 18F-FE-PE2I PET) in PD-depression with or without anhedonia. We hypothesize that lower DAT-availability (i.e. more…
(Short) stay and, if possible, treatment at the PMU, will give an improvement in regular psychometrics or at least in some of them.
Early diagnosis of cystic fibrosis (CF) and primary ciliary dyskinesia (PCD) combined with swift identification and treatment of pulmonary infections is important for the preservation of pulmonary function, quality of life and life expectancy. A…
Accumulating data from both patients and animal models indicates that imbalances in the composition of the gut microbiota are related to obesity and its associated diseases However, the exact role of the microbiota and the mechanism mediating its…
We expect that CAU with adjunct evidence-based prescription of exercise is more effective than CAU alone in reducing depressive symptoms in patients with major depressive disorder.
The combination of fibrinogen concentrate with FFP transfusion to patients with massive post/peri-operative bleeding problems is a better alternative than FFP transfusion alone, due to the prevention of dilutional coagulapathy.
Increase in cycle endurance time after pulmonary rehabilitation using NHF oxygen supplementation will be larger compared to conventional oxygen delivery systems.
Our hypothesis is that less sugar-sweetened beverages will be purchased in both tax conditions compared to the control condition, and that the nutrient profiling tax condition will affect healthiness of the total shopping basket and total purchased…
Addition of 90Y-ibritumomab tiuxetan after R-PECC is feasible and the efficacy meets expectations as described in the protocol.
Intensive pharmacovigilance in high-risk patients, much less intensive pharmacovigilance in low-risk patients and an education program for prescribers will lead to a reduction of medication related events (death, disability, increased hospital stay…
To asses the proportion of patients with pseudotumor observerd on MARS-MRI images.