6329 resultaten
This is an exploratory study to further delineate the microenvironment of the PT and (S)LNs in cervical cancer.
We hypothesize that patients with craniopharyngioma and hypothalamic obesity have less efficacy of bariatric surgery compared to controls from a 'general' obese population
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Anti-nociception is an existing or attainable state of pain modulation that can be reached by specific pharmacological agents coupled to individual patterns of pain modulation. Being in, or shifted into anti-nociception state of pain modulation,…
Approximately 2% of the Dutch elderly population suffers from a major depressive disorder (MDD). Due to a depressed mood and a diminished interest in nearly all activities, MDD has serious consequences for daily living (e.g. withdrawal from social…
Shoulder pain is related to somatosensory and nociceptive changes in the acute phase after stroke. These changes may indicate the involvement of specific mechanisms (nociceptive, neuropathic) of post-stroke shoulder pain. Changes may either precede…
Surgical and radiation oncologists aim for the best cosmetic outcome and QoL of each patient, without compromising oncological safety. However, especially in the light of current oncoplastic reconstructive surgery techniques, it has not yet been…
This study will address the primary null hypothesis that there is no difference in inter-observer variability for the Geissler classification of SL pathology between surgeons that viewed only radiocarpal and those who viewed radiocarpal and…
We assess the prevalence and seriousness of DDIs among ambulatory cancer patients on anti-cancer treatment.
Has the Emotion Regulation Training for adolescents a surplus value compared to treatment as usual?
Using low field stimulation on two brain regions simultaneously, we aim to specifically alter the connectivity between one or more pairs of brain areas.
We expect after FGC: - increased child safety (in terms of less supervision orders; and less or shorter out of home placements) - increased commitment of the broader social network of the family - increased perceived control over problems/sense of…
In general we hypothesize that the characteristics of voice hearing in patients with schizophrenia spectrum disorders with a childhood trauma history are not significantly different from those in patients with a dissociative identity disorder,…
A possibly competitive inhibition between imatinib and rosuvastatin as substrates for the same solute carriers (i.e. OATP 1A2 and ABCG2) may result in drug-drug interactions and altered pharmacokinetics of imatinib.
The aim of the current study is to investigate and compare the actual risk of aggression and the assumed risk of aggression (by staff) in the forensic psychiatric and regular psychiatric population. The hypothesis is that the actual risk of…
Prior studies have shown reagent dependent differences in sensitivity to circulating clotting factor VII (FVII). This reagent dependent sensitivity to FVII can explain the INR differences between laboratory methods and point-of care devices found in…
In vulvar cancer patients with a macrometastasis in the sentinel lymph nodes, chemoradiation is as effective as an inguinofemoral lymphadenectomy, but is associated with less treatment-related morbidity.
Whether antibiotic guidance by procalcitonin measurements are able to reduce antibiotic usage and duration in Dutch intensive care units.
Leflunomide is able to reduce the relapses, the glucocorticoid use and the adverse events associated with glucocorticoid s use in PMR patients.
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