Many authors have advocated different methods of treating alveolar osteitis. One of these is the use of 0,12% chlorhexidine before and after the removal of the third molar. Despite many years of research, however, little progress has been made and…
ID
Source
Brief title
Condition
- Head and neck therapeutic procedures
Synonym
Research involving
Sponsors and support
Intervention
Outcome measures
Primary outcome
Does rinsing with chlorhexidine after lower third molar removal effect the
postoperative complications?
Secondary outcome
• Does rinsing postoperative with chlorhexidine lower the postoperative pain
intensity, measured with the VAS scale, after surgical removal of impacted
lower third molars
• Does rinsing postoperative with chlorhexidine lower the need for analgesics
postoperative?
• Does rinsing postoperative with chlorhexidine reduces the number of
out-patient contacts?
• Does rinsing postoperative with chlorhexidine reduces / affect the number of
days of leave from work or study?
Background summary
One of the most common postoperative complications after the removal of a third
molar is a condition known as dry socket. This term has been in use since 1896.
Since then several other terms have been used, including alveolar osteitis,
postoperative alveolitis, alveolitis, sicca dolorosa and fibriniolytic
alveolitis. Bim labelled the complication fibrinolytic alveolitis which is the
most accurate of the terms, but also the least used. The condition has
generally been characterised by delayed healing associated with degradadtion of
clot, and is usually accompanied by persistent, radiating, pain
postoperativively in and around the extraction site that is not easily relieved
by analgesics6.
Because of the pain, swelling and trismus, patients also tend to have a greater
need for painkillers. If it is possible to reduce the amount and severity of
postoperative pain felt by patients the postoperative period would be more
endurable, the quality of life will be less affected, and in addition to this
it is possible that the amount of analgesics taken by patients after surgery
could be lowered7. It can be a burden for both patients an surgeons and my
result in a loss of productivity because at least 45% of patients require
multiple visits to the surgeon.
Study objective
Many authors have advocated different methods of treating alveolar osteitis.
One of these is the use of 0,12% chlorhexidine before and after the removal of
the third molar. Despite many years of research, however, little progress has
been made and so a study with large enough sample and standard outcome measures
is warranted.
Goal of this study is assess the effect of postoperative use of chlorhexidine
on postoperative complaints after surgical removal of a lower third molar.
Study design
Double blind, randomized controlled clinical trial
Intervention
Rising with chlorhexidine rinsing solution for one week three times a day
Study burden and risks
The risks of the use of chlorhexidine rinsing solution are very low. Patients
can have a temporary disturbed taste and temporary discoloring of the teeth
Kuyerhuislaan 3c
Zwolle 8024 PC
NL
Kuyerhuislaan 3c
Zwolle 8024 PC
NL
Listed location countries
Age
Inclusion criteria
patients over 18 years of age referred for removal of a wisdom tooth in the
mandible. Patient has ASA I.
Exclusion criteria
- Patient is younger than 18 years
- Patient has an ASA of II,III en IV
- Patient has only one maxillary third molar that needs to be extracted/removed
- Patient has an active pericoronitis
- Patient has trismus
- Patient has chronic pain
- Patient is pregnant
- Patient has a known allergy for ibuprofen of other NSAID*s
- Patient has a known allergy for articaine of epinefrine
- Patient has a known allergy for gentamicin
- Intra-operative compliations for example excesive bleeding
Design
Recruitment
Followed up by the following (possibly more current) registration
No registrations found.
Other (possibly less up-to-date) registrations in this register
In other registers
| Register | ID |
|---|---|
| CCMO | NL71727.075.20 |
| OMON | NL-OMON27406 |