96 results
We hypothesize that the underlying mechanisms of the varying response in multiple parameters within an individual can be attributed to variability in the causal path between drug administration, drug tissue distribution, and tissue receptor…
Knee OA is characterized by the presence of crepitus (knee sounds). Therefore, this device is able to record these sounds, while the subject is doing a knee movement, and screen for the presence or absence of osteoarthritis.
To investigate whether patients prefer to be approached by mailed questionnaires for annual follow-up assessment after PCI procedures versus telephone interviews or email-based follow-up
It will be investigated whether passive leg raising and stroke volume variations can be used in predicting renal responses to fluid administration. Our hypothesis is that dynamic predictors of cardiac fluid responsiveness can predict an increase in…
Youth at intermediate vocational education (ROC's) show excessive alcohol and drug use, which can have various detrimental consequences. For this vulnerable group of youngsters a targeted, multicomponent plan of attack was developed in…
a. Ascorbic acid in combination with metformin (500mg BD) improve the glucose tolerance with a daily dose of 500mg over a period of 12 months. b. Ascorbic acid with metformin reduce the adverse effects/events. c. Acetylesalicylic acid in…
To determine the feasibility of a home based rehabilitation program delivered by means of a tablet-pc for patients after THA To get a first impression of the clinical effectiveness of the rehabilitation program
EN - Unrelieved chronic pain represents a major problem for individual patients and is also a socio-economic burden for health services and the community at large. Although the etiology of musculoskeletal chronic pain following trauma is not well…
1) Feasibility of EMDR in older adults (age 60+) is comparable to younger adults (age 20-60); 2) EMDR treatment of PTSD results in improvement of PDs and improvement of cognitive functioning. 3) Somatic and psychiatric comorbidity are negatively…
The main hyothesis of the experiments is that a dual action antidepressant (duloxetine) modulates functions in specific brain areas involved in the processing bias of emotional stimuli in the context of neutral versus depressed mood.
personality traitsinfluence the assessment of echocardiography images with respect to evaluation of LV EF and image quality.
We hypothesize that TIPS placement has an significant effect on drug metabolism and bile acid metabolism.
The aim of this study is twofold: 1)To assess the effectiveness of a CPG converted into a CDSS, in actually preventing the development of WSLs during orthodontic treatment with fixed appliances compared to usual preventive measures. 2)To evaluate…
1. To establish in a randomised controlled trial if screening for lung cancer by multi-slice low-dose CT in high risk subjects will lead to a 25% decrease in lung cancer mortality; 2. To estimate the impact of lung cancer screening on health…
Onlay and sublay mesh reinforcement after midline laparotomies in patients with an increased risk for the development of incisional hernias (IHs) resulted in less IHs compared to patients that received the conventional closure technique at two years…
The primary objective of this study is to validate MRI as a functional measuring device for directly monitoring gastric emptying in vivo
Primary Objective: Investigate the effect of modafinil (200 mg) and caffeine (300 mg) on vigilance in low, medium and high caffeine consumers during the circadian trough in order to determine: - To what extend vigilance during the circadian trough…
The hypothesis is that the metabolic age, representing a health score will be lower after nine weeks of personalized dietary intervention compared to the control arm (without dietary advice). The phenotypic flexibility or resilience (the ability to…