96 results
The primary aim of the study is to evaluate whether the blended care intervention Living to the Full 55+ as an indicated prevention for anxiety complaints is more (cost-) effective than Treatment As Usual (TAU). We hypothesize that in comparison to…
Primary hypotheses The primary hypothesis of the present study is that included patients who receive continuous or intermittent oxygen and bilevel positive pressure ventilation during fixed work rate treadmill exercise tests have shorter recovery…
The results from this trial will provide evidence on whether structured risk assessments and customized maternity care for high-risk pregnant women by maternity care providers is feasible in terms of effectiveness, especially regarding maternal…
We expect that depressive adolescents will show a stronger increase in heart rate during, as well as a slower recovery afterwards, when they are left in the game or when they encounter fearful stimuli compared to non-depressive adolescents. Finally…
Morbidity in the post-operative phase of pulmonary surgery is characterised by impairment due to pain, dyspnoea and loss of exercise tolerance. We demonstrated previously that rehabilitation after thoracotomy is limited due to pain. Since minimal…
Assess the safety and tolerability of single ascending IV bolus doses of ABP-700
Approximately 1/3 of persons with IGT develops type 2 diabetes mellitus in 5-10 years time. Acarbose is an alpha-glucosidase inhibitor decreasing post-prandial glucose levels, without the risk of hypoglycemia. The prevention of diabetes with…
We hypothesize that early programming leads to differential brain function. A result of these changes in brain function will be differences in energy expenditure and food intake leading to different eating behaviour and differences in sensitivity to…
Primary objective: To determine the safety of once daily inhalation of the recommended daily dose of tobramycin with the Akita® and the PARI-LC® Plus nebulizer in patients with CF. Systemic absorption can be used as surrogate parameter for safety.…
The module “Working with parents in creating a pleasant school” positively effects the attitudes, efforts and self-efficacy of teachers, parents, students in (jointly) counteracting bullying.
It is hypothesized that chicken eggshell membrane is effective in the regeneration of cartilage and/or immunomodulation (oral tolerance), and as such positively affects pain and stiffness in joints commonly affected in arthritis
The primary objective of the study is to examine whether the WhiteTeeth app used by orthodontic patients aged 12 to 16 improves oral health behavior and oral hygiene. Primary outcomes of this RCT are dental plaque levels, gingival bleeding upon…
The correlations between the three measurement instruments are moderate (r = 0,41 to 0,60).
a clinical evaluation of the two drop-in gamma probe prototypes for their ability to localize the sentinel node(s) during robot-assisted sentinel node biopsy of the prostate.
The doctor-patient-relation is a powerful and important tool in the complex care for patients with (chronical) MUS.
To assess the safety and tolerability of intravenous (IV) infusion doses and infusion dosing methodologies of ABP-700 alone or in the presence of pre-medications commonly used in the monitored anesthesia care (MAC) setting