50 results
Primary Objectives:- Determine the effect of pulmonary vasodilatation on indexed cardiac output during simulated exercise.- Characterization of structural properties of small pulmonary arteries.Secondary Objectives: - Investigate the effect of…
1. To characterize and compare RV myocardial structure, contraction patterns, and functional capacity of (A) PH patients (group 1 or 4, the latter are to be inoperable), (B) patients with pressure overloaded RV due to CHD and (C) healthy controls. 2…
To evaluate the clinical usefulness of the VU-AMS in pediatric cardiology.To validate and improve the measures of stroke volume from the VU-AMS device in a clinical population. VU-AMS stroke volume measures will be compared with stroke volume…
Identify congenital heart disease patients with exercise-induced pulmonary arterial hypertension. Analyze changes in pulmonary arterial pressures at peak exercise in patients with exercise induced pulmonary arterial hypertension before and after…
To establish benchmark values in healthy control fetuses, to compare these with our cohort of fetuses with severe CHD.
The primary objective of the study is to determine whether exercise training exerts a long term effect on maximal exercise capacity, clinical events, sports participation, serum NT-proBNP and quality of life in adults with a systemic right ventricle…
Objectives:Medical: What is the effect of an exercise training program in children and young adults (up to 20 years of age) who have undergone treatment for ConHD (tetralogy of Fallot or Fontan procedure) on: a) aerobic fitness, b) ventricular size…
In patients long-term after AVSD correction the objectives are:1) To evaluate myocardial function using novel echocardiographic techniques.2) To study atrial en ventricular size and function in relation to quantification of AVV function with the use…
The main objectives are 1) is to evaluate the prevalence of cardiac complications long-term after ASO by investigation of cardiac function as well as clinical outcome and to determine which factors (associated with life style or operative techniques…
1. To evaluate the clinical usefulness of STIC with post-process rendering capability. Our goal is to investigate whether STIC gives more accurate information about a suspected cardiac anomaly, compared to conventional 2D ultracardiography.2. To…
Routine evaluation of dyssynchrony in pediatric patients with cardiac disease is feasible using standard and novel echocardiographic techniques. The extent of cardiac dyssynchrony and its influence on cardiac function differs between groups of…
1. To investigate the causal relationships between atherosclerotic disease risk and existing, long-term cyanotic heart disease. 2. To differentiate these causal relationships according to each of the assessed risk factors and their relationship with…
- To determine physical fitness in children with a congenital heart disease (ventricular septum defect, atrium septum defect, tetralogy of Fallot, transposition of large arteries and patients after a (modified) Fontan-operation) and to compare…
The aim of this study is 1. to compare scarformation in two different operative protocols in a prospective manner of children who undergo sternotomy because of cardiologic disease. 2. to differentioate scar pain from sternotomy pain. 3. to estimate…
The aim of the present study is to evaluate the effect of exercise training on exercise capacity, serum NT-proBNP levels and quality of life in adult patients with a systemic right ventricle.
The primary aim of this study is to assess the applicability of RT3DE for the evaluation of left ventricular function in daily clinical practice of a pediatric cardiology service.
Primary Objectives: To prospectively investigate the changes in cardiac parameters (echocardiography, NT-pro-BNP) and uteroplacental flow (pulsatility index, diastolic notching) during/after pregnancy in women with CHD and compare these changes with…
An explanation of the complete spectrum of anomalies seen in fetuses with increased NT could be a disturbed endothelial differentiation related to the cardiovascular development. Cardiac defects form the severe end of the spectrum. More data, both…
This study observes the immune system of children and adults who have been without a thymus for 3 to 30 years. Our objective is to study the role of the thymus in the developing immune system. In addition this study will give insight in the long…
Speckle Tracking Imaging is a relatively new echocardiographic technique to quantify the left ventrikular twist and untwisting movement. Several populations like healthy adults and patients with hypertension, myocardial infarction or valvular…