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Study FDC114615: Comparative efficacy of DuodartTM plus lifestyle advice versus watchful waiting plus lifestyle advice with step-up therapy to tamsulosin in the management of treatment naïve men with moderately symptomatic benign prostatic hyperplasia and prostate enlargement.

Primary: Effectivity. Secundary: Effectivity (questionnaires, progression, surgery), safety and tolerability.

POETIC: Point Of carE Testing for urinary tract Infection in primary Care:
Study Stages 3 & 4: Randomised controlled trial and post-RCT observational study

The overall aim of our study is to evaluate the management of suspected uncomplicated UTI in women presenting in primary care through use of a novel point of care test (POCT, Flexicult). This study is being carried out in 4 European networks: Wales…

A Double blind, Randomized, Placebo-Controlled Study Evaluating the Safety and Effectiveness of Cook MyoSite Incorporated AMDC in Female Patients with Stress Urinary Incontinence

The study will evaluate the injection of AMDC for Urinary Sphincter Repair (USR) compared to a placebo dose, with the hypothesis that one or two treatments of AMDC is statistically superior to placebo at 12 months following the initial treatment.

Solace European Confirmatory Trial: An Evaluation of the Solace Bladder Control System in the Treatment of Female Subjects with Stress Urinary Incontinence.

To confirm previous study results using a Solace Balloon and to support future marketing efforts in the European Union and provide data for publications.

Urethral suspension using vas deferens for prevention of urine incontinence after robot-assisted laparoscopic prostatectomy (RALP)

Improve postoperative urine continence after prostatectomy for prostate cancer.

Pelvic floor exercises compared to medication in the treatment of older men with lower urinary tract symptoms (LUTS) in general practice. The FLOW study.

The primary objective of the study is to study the effects of pelvic floor physiotherapy compared to treatment with α1-blocking agents in men with lower urinary tract symptoms.The secondary objective is to study the effects of the two therapies on…

Relevance of Biomarkers and Clinical Predictors of Outcome in Unselected Population with Febrile Urinary Tract Infection at Primary Care and Emergency Department in a Prospective, Randomized Cohort Trial Comparing Short (7 days) Antibiotic Treatment with Conventional Treatment (14 days)

To assess clinical parameters and biomarkers in blood and urine in predicting bacteremia, need for hospital admission, clinical and bacteriologic cure and mortality in patients with fUTI.To determine whether a 7-day duration of antibiotic treatment…

Prevention of recurrent urinary tract infections by multi-drug resistant bacteria, by intravesical administration of gentamicin.

Objective: The main objective is to demonstrate superiority of the intravesical overnight instillation of gentamicin versus oral antibiotic prophylaxis in reducing the number of recurrences of UTI and extending the time-interval to a next UTI, in…

Uremic Toxins, Cardiovascular Effects and Physical Activity in Intensive Hemodialysis

The primary objective of this study is to compare vascular biology (vascular markers and endothelial microparticles) and cardiovascular effects (volume status, blood pressure, pulse wave velocity and microcirculation) in conventional hemodialysis (…

Cognitive bladder training versus rectal washout training for girls with recurrent urinary tract infections and urinary incontinence

Research question: is primary aggressive treatment of constipation with rectal wash-out in girls with NNBSD at least equally effective as usual care?

The role of the pelvic floor in Lower Urinary Tract Symptoms (LUTS) in men.

The main objective of this study is to assess the effectiveness of pelvic floor muscle therapy in comparison with α-blockers, in men with LUTS. The second objective is the validation of the questionnaire (MPFS) in this group of patients

Antibiotic prophylaxis in prevention of urinary tract infections caused by removal of a bladder catheter in children

The goal of this study is to determine whether a short course of amoxicillin/clavulanic acid reduces the number of urinary tract infections in children that have been catheterized during a short period.

Multicentered randomized controlled trial to test the cost effectiveness of urodynamics in women with symptoms of stress urinary incontinence in whom surgical treatment is considered.

To test the value of preoperatively performed urodynamics with regard to outcome of surgery for stress urinary incontinence (SUI) and to examine whether not performing urodynamics preoperatively is more cost effective than performing urodynamics…

The central cause of overactive bladder, a pilot study

The objective of this study is to proof the presence of lesions in the brain of patients with overactive bladder and urge-incontinence (OAB wet) as a central cause of this disorder. This survey is a pilot investigation for a larger study on the…

The effects and costs of cranberry use to prevent symptomatic urinary tract infections in nursing home residents.

To assess the effects and costs of cranberry use to prevent symptomatic UTIs in nursing home residents.

Clinical parameters and biomarkers in blood and urine as predictors for bacteremia, hospital admission, morbidity and outcome in patients with complicated urinary tract infections.
A study in primary care, the medicine emergency room and ICunit.

Establish relevance of a clinical scoring system, and of established and to be identified biomarkers in blood and urine for clinical course and clinical and microbiological outcome of patients with a complicated urinary tract infection, treated in…

A phase II, randomized, double-blind, placebo-controlled trial investigating the efficacy and safety of Org 3236 tablets in men with Lower Urinary Tract Symptoms (LUTS) suggestive of Benign Prostatic Hyperplasia (BPH)

The objectives are to evaluate:- The effect of Org 3236 on prostate volume compared to placebo;- The effect of Org 3236 on LUTS compared to placebo;- The effect of Org 3236 on urinary flow and postvoid residual volume compared toplacebo;- The effect…

Eye Movement Desensitisation and Reprocessing (EMDR) treatment for persistant nocturnal enuresis

The aim of the study is to investigate if alarm treatment in combination with EMDR is a better method for persistent enuresis nocturna than only alarm treatment.Subquestions: 1. What is the success percentage of EMDR with alarm treatment? 2. If EMDR…

Electromyographic feedback in the treatment of the pelvic floor in Lower Urinary Tract Symptoms (LUTS) in men.

The main objective of this study is to assess the additive effect of EMG-feedback in the treatment of LUTS in men.

Perioperative urinary output and course of diuresis during outpatient treatment under general anesthesia.

Main question:Does a restrictive fluid management during general anesthesia lead to less urinary production?Sub questions:Does a fluid management with colloid fluid during general anesthesia lead to a change in urinary production?Does a different…